Haskap Berries and Gut Health Study
This study is looking at how Haskap berries affect your gut health and overall well-being. Researchers want to understand how the natural compounds in Haskap berries interact with the bacteria in your gut (gut microbiota) and if this leads to better health. You would either receive a Haskap berry smoothie or a placebo smoothie (a smoothie without the active berry ingredients but with similar carbohydrates). The study will measure changes in your gut bacteria, inflammation levels, and cholesterol (lipid panel) after 8 weeks. This study is for people aged 35 to 65, and includes both those who are generally metabolically healthy and those with some metabolic health concerns, such as specific waist circumference, blood pressure, or blood sugar levels.
- Study design
- This is a randomized, triple-blind, placebo-controlled study with 120 participants. Participants will be assigned to one of four groups, receiving either a Haskap berry smoothie or a placebo.
- What's involved
- Participants will be assessed before and after 8 weeks of intervention, which includes measurements of health biometrics, fat oxidation, gut microbiome composition, inflammation, and gut and serum metabolites.
- Compensation
- Not stated in the trial record.
- Follow-up
- The primary endpoints are measured at 8 weeks, indicating the duration of the intervention period.
AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.
Gut Microbiota-dependent Health Impacts of Haskap Berries
At a glance
Conditions
Where it's being run
1 sites across 1 statesStudy leadership
- Mary P Miles, PhD · PRINCIPAL_INVESTIGATOR · Montana State University
Who to contact
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Do you actually qualify for this trial?
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Inclusion
Exclusion
What this trial measures
- 16 subunit ribosomal ribonucleic acid (16S rRNA) gut microbial composition8 weeks
fecal microbial composition
- Inflammation (pg/mL)8 weeks
Serum interleukin (IL) IL-1B, IL-6, IL-10, IL-17, IL-23, tumor necrosis factor alpha (TNF-alpha), granulocyte-macrophage colony-stimulating factor (GM-CSF), interferon gamma (IFN-gamma)
- Lipid Panel (mg/dL)8 weeks
Serum triglycerides (TG), low-density lipoprotein (LDL) cholesterol, high-density lipoprotein (HDL) cholesterol, total cholesterol (CHOL), glucose (GLU)
- F2 isoprostanes8 weeks
urine
- Untargeted metabolomic analysis8 weeks
Serum metabolome
- Untargeted metabolomic analysis8 weeks
Fecal metabolome
- Exercise Induced Fat Oxidation8 weeks
Measurement in g/min of fat being utilized during exercise at 40-60% of the participants estimated VO2max