Cognitive Assessment Tools for Huntington's Disease
This study is looking at two cognitive tests, the Coding Test and the Self-Administered Gerocognitive Examination (SAGE), to see how well they work for people with Huntington's Disease (HD). These tests have been used for other brain diseases, but more information is needed for HD. The study aims to see if these tests could be helpful for screening or in future clinical trials for HD. You may be able to join if you are between 30 and 65 years old, have a genetic diagnosis of HD (CAG repeat size of 40 or more), and a clinical diagnosis of HD (Diagnostic Confidence Level of 4). The study will compare scores from the Coding Test to the Symbol Digit Modality Test (SDMT), and SAGE scores to the SDMT and Stroop Word reading scores, all measured during a single visit.
- Study design
- This is an observational study, meaning it looks at existing conditions without giving new treatments. It plans to include 76 participants.
- What's involved
- You would have a one-time visit lasting about 1 to 1.5 hours. During this visit, you would have your vital signs checked, and complete cognitive, functional, and motor assessments.
- Compensation
- Not stated in the trial record.
- Follow-up
- Your participation involves a single visit, and the primary endpoints are measured at that one-day visit.
AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.
Cognitive Assessment Tools for Huntington's Disease.
At a glance
Conditions
NCT06546488
Where you'd take part
This study runs at 1 site. They're the same protocol — you choose where, and that choice sets who your contact draft is addressed to.
The Ohio State University Wexner Medical Center
Columbus, Ohiono site contact published
Recruiting
Sites open and close at different times, so the status above is per site — it can differ from the study's overall status.
Who to contact
Opens a ready-to-send draft in your own email app — review before sending.
What this trial measures
- Symbol Digit Modality Test (SDMT) compared to the Coding TestOne day visit
Comparison of scores on Symbol Digit Modality Test (SDMT) and Coding Test. Associations will be investigated using Spearman correlations.
- Self-Administered Gerocognitive Examination (SAGE) score compared to the Symbol Digit Modality Test (SDMT) and the Stroop Word reading scoresOne day visit
Comparison of SAGE score with the SDMT and the Stroop Word reading scores. (The two neuropsychological scores used in the UHDRS that have shown the best correlation with HD disease onset and progression). Associations will be investigated using Spearman correlations.