Time-Restricted Eating for Alzheimer's Disease (TREAD) Study

This study, called TREAD, is looking at whether a specific eating pattern called time-restricted eating can help people with Mild Cognitive Impairment (MCI) or early to moderate Alzheimer's disease (AD). Time-restricted eating means you fast (don't eat or drink anything with calories) for 14 hours each night, with no food after 8 PM. The goal is to see if this can reduce sleep problems, slow down memory decline, and impact the disease itself. Researchers also want to find out if it's practical for older adults to stick to this eating schedule for 3 to 6 months. The study aims to enroll 60 participants aged 60 and older who are in good general health or have been diagnosed with MCI or AD.

Study design
This interventional study plans to enroll 60 participants. It is not specified if it is randomized or blinded.
What's involved
You would need to provide signed consent and be willing to follow all study procedures for the duration of the study, including practicing 14 hours of nightly fasting.
Compensation
Not stated in the trial record.
Follow-up
Feasibility of the intervention will be assessed at 3 and 6 months.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.

NCT06548191

TREAD: Time Restricted Eating Intervention for Alzheimer's Disease

Recruiting
PHASE1Ages 60+InterventionalTreatment
University of California, San Diego
~60 participants
Updated 2026-05-26 on ClinicalTrials.gov
What's tested:Time-restricted eating

At a glance

Recruiting sites
1 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Feasibility: assessed by computing the number of nights achieving the goal fasting time of 14 h.
Measured over 3 and 6 months
Mild Cognitive Impairment
Alzheimer Disease
Alzheimer's Disease
1 sites across 1 states
California1
  • Paula Desplats, PhD · PRINCIPAL_INVESTIGATOR · University of California, San Diego

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  • Feasibility: assessed by computing the number of nights achieving the goal fasting time of 14 h.3 and 6 months

    Test the feasibility of a Time-restricted eating intervention in patients with MCI or AD by quantification the number of days during the intervention period when the particpants reached the goal intervention fasting time of 14 h, b) increased fasting of \>12 h and \<14 h.