NCT06549413

18F-FSPG PET/CT as a Non-Invasive Imaging Biomarker for Treatment Response to Chemoradiation in Esophageal Cancer

Terminated
Not specifiedAges 18+Observational
M.D. Anderson Cancer Center
~9 participants
Updated 2026-08-13 on ClinicalTrials.gov
What's tested:Non-Interventional Study

At a glance

Recruiting sites
0 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Safety and adverse events (AEs)
Measured over Through study completion; an average of 1 year.
Esophageal Carcinoma

NCT06549413

Where you'd take part

This study runs at 1 site. They're the same protocol — you choose where, and that choice sets who your contact draft is addressed to.

  • M D Anderson Cancer Center

    Houston, Texasno site contact published

Sites open and close at different times, so the status above is per site — it can differ from the study's overall status.

  • Steven H Lin, MD, PHD · PRINCIPAL_INVESTIGATOR · M.D. Anderson Cancer Center

This trial hasn't published a contact. View it on ClinicalTrials.gov

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Eligibility criteria

Inclusion

\* ≥ 18 years of age
Patients with locally advanced esophageal cancer
Patients with untreated documented carcinoma of the esophagus that is \> 2 cm who are going to receive systemic therapy concurrently with radiation as primary therapy
Ability to provide written informed consent in accordance with institutional policies
Female subjects of childbearing potential must have a negative serum or urine pregnancy test within 1 week of the proposed investigational PET/CT scan(s) prior to injection of the investigational radiopharmaceutical

Exclusion

\* Body weight ≥ 400 pounds or body habitus or disability that will not permit the imaging protocol to be performed
Pregnant or lactating females
Have an allergy to intravenous contrast
eGFR \< 30
  • Safety and adverse events (AEs)Through study completion; an average of 1 year.

    Incidence of Adverse Events, Graded According to National Cancer Institute Common Terminology Criteria for Adverse Events (NCI CTCAE) Version (v) 5.0