Small Nerve Fiber Activity in Carpal Tunnel Syndrome with Physical Therapy

This study is looking at how standard physical therapy affects small nerve fibers in people with Carpal Tunnel Syndrome (CTS). CTS is a condition causing pain and numbness in the hand. Doctors usually diagnose CTS using clinical exams and electrodiagnostic tests, but these tests mainly check large nerve fibers. This study uses Quantitative Sensory Testing (QST), a series of tests, to assess smaller nerve fibers (A-delta, C-fibers, and A-beta) which are also involved in CTS. The study will see if physical therapy changes the activity of these small nerve fibers and how those changes relate to your symptoms. You may be able to join if you are 18-65 years old, have CTS symptoms, and are willing to attend physical therapy.

Study design
This interventional study plans to enroll 48 participants to receive standard physical therapy.
What's involved
Participants will receive physical therapy and have Quantitative Sensory Testing (QST) from enrollment until the end of the study at 12 weeks.
Compensation
Not stated in the trial record.
Follow-up
Participants will be followed from enrollment until the end of the study at 12 weeks.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.

NCT06550284

Small Nerve Fiber Activity in Patients with Carpal Tunnel Syndrome Assessed Via Quantitative Sensory Testing

Recruiting
NAAges 18–65InterventionalTreatment
Brooke Army Medical Center
~48 participants
Updated 2025-02-05 on ClinicalTrials.gov
What's tested:Physical Therapy

At a glance

Recruiting sites
1 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Quantitative Sensory Testing (QST)
Measured over From enrollment until the end of the study at 12 weeks
Carpal Tunnel Syndrome

NCT06550284

Where you'd take part

This study runs at 1 site. They're the same protocol — you choose where, and that choice sets who your contact draft is addressed to.

  • Brooke Army Medical Center

    San Antonio, Texasstudy coordinator listed

    Recruiting

Sites open and close at different times, so the status above is per site — it can differ from the study's overall status.

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  • Quantitative Sensory Testing (QST)From enrollment until the end of the study at 12 weeks

    QST is a test method that measures sensory thresholds for temperature sensations, touch, vibration, and pain and is described in section 10.1. All thermal testing (CDT, WDT, CPT, and HPT) will be performed via the TSA 2 Thermosensory Stimulator.