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Cybersickness Prevention in Virtual Reality for Healthy Volunteers

This study is testing a new software called Motion Reset, designed to reduce "cybersickness" (similar to motion sickness, with symptoms like eye strain, nausea, or dizziness) that some people experience after using virtual reality (VR). We want to see if Motion Reset can effectively prevent these symptoms. You may be able to join if you are a healthy adult between 18 and 60 years old. Success in this study will be measured by how much participants report feeling cybersickness during and after using VR. The current recruitment status is unclear.

Study design
This is an interventional study with 150 planned participants. Participants will be randomly assigned to receive Motion Reset, a placebo (a similar VR experience without the active intervention), or no treatment.
What's involved
You will have one clinic visit lasting about 1 hour. During this visit, you will answer questions, learn to use a VR headset, and play a VR game.
Compensation
Not stated in the trial record.
Follow-up
Your self-reported cybersickness will be measured during and after VR use, but the total follow-up duration is not specified.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.

NCT06552754

Cybersickness Prevention and Mitigation in Virtual Reality for Healthy Volunteers

Recruiting
NAAges 18–60InterventionalPrevention
National Human Genome Research Institute (NHGRI)
~150 participants
Updated 2026-09-10 on ClinicalTrials.gov
What's tested:Motion ResetPlacebo

At a glance

Recruiting sites
2 of 2 listed sites are recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
self-reported cybersickness
Measured over during and after VR use

Conditions

Healthy Volunteers
Virtual Reality

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Healthy Volunteers

NCT06552754

Where you'd take part

This study runs at 2 sites. They're the same protocol — you choose where, and that choice sets who your contact draft is addressed to.

  • National Institutes of Health Clinical Center

    Bethesda, Marylandstudy coordinator listed

    Recruiting

  • Iowa State University

    Ames, Iowano site contact published

    Recruiting

Sites open and close at different times, so the status above is per site — it can differ from the study's overall status.

Study leadership

  • Susan J Persky, Ph.D. · PRINCIPAL_INVESTIGATOR · National Human Genome Research Institute (NHGRI)

Who to contact

Susan J Persky, Ph.D.
[email protected]
(301) 451-1268
Email the study team

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Eligibility criteria

Inclusion

Provision of signed and dated informed consent form
Stated willingness to comply with all study procedures and availability for the duration of the study
Aged 18-60
Ability to read, speak, and write in English
Normal or corrected-to-normal hearing
Normal vision or corrected-to-normal without use of glasses. Contact lenses for corrective purposes are acceptable.

Exclusion

Reporting motion sickness propensity of 0, 9 or 10 on a 0-10 scale where 0 =never experience motion sickness and 10 = experience motion sickness very frequently (self-assessed by participants).
Reporting a history of photo-sensitive seizure disorders, vestibular disorders and/or other conditions that may make participants prone to nausea, dizziness, vertigo, ataxia, or incoordination.
Known pregnancy
Reporting current use of medication or supplements that inhibit nausea, e.g., Zofran/ondansetron, Phenergan/promethazine

What this trial measures

  • self-reported cybersicknessduring and after VR use

    Assessed on numerical scale