Home-based Cycling for Multiple Sclerosis and High Blood Pressure
This study is looking at whether 12 weeks of home-based cycling exercise can improve blood pressure, thinking skills (cognition), and walking ability in people with multiple sclerosis (MS) who also have high blood pressure (hypertension). You would use a special stationary bike at home, gradually increasing your exercise time and effort. The study wants to see if this cycling can improve blood pressure by helping blood vessels widen, and if better blood pressure then helps with thinking and walking. To join, you need to be an adult (18+) with a confirmed MS diagnosis (Expanded Disability Status Scale scores of 4-6.5) and high blood pressure (systolic blood pressure > 120 mmHg or diastolic blood pressure > 80 mmHg). The study plans to enroll 80 participants, but its current status is unclear.
- Study design
- This is an interventional study comparing home-based aerobic training (cycling) to a home-based stretching program. It plans to enroll 80 participants.
- What's involved
- You would participate in a 12-week home-based cycling program, progressing from 10 to 40 minutes per session. Your information processing speed and walking ability will be measured at the beginning and within 5 days after the program ends.
- Compensation
- Not stated in the trial record.
- Follow-up
- Your information processing speed and walking ability will be measured within 5 days after completing the 12-week training intervention.
AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.
Vascular Mechanisms, Functional Outcomes, & Exercise Among Persons With Multiple Sclerosis With Hypertension
At a glance
Conditions
Where it's being run
1 sites across 1 statesStudy leadership
- Bo Fernhall, PhD · PRINCIPAL_INVESTIGATOR · University of Massachusetts, Boston
- Tracy Baynard, PhD · PRINCIPAL_INVESTIGATOR · University of Massachusetts, Boston
Who to contact
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Do you actually qualify for this trial?
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Inclusion
Exclusion
What this trial measures
- Information processing speedBaseline, pre-intervention/BICAMS; Within 5 days after completion of the training intervention/BICAMS
The Brief International Cognitive Assessment (BICAMS) battery tests, including the Symbol Digit Modalities Test (SDMT) and California Verbal Learning Test-II (CVLT-II)
- Timed 25-Foot WalkBaseline, pre-intervention/25-Foot Walk; Within 5 days after completion of training intervention/ 25-Foot Walk
Measurement of mobility disability