Outcomes of Clareon PanOptix Pro in Patients With Prior Myopic Refractive Surgery

This study is looking at how well a specific type of lens, the Clareon PanOptix Pro IOL, works for people having cataract surgery who have previously had vision correction surgery like LASIK or PRK. You might be able to join if you are an adult aged 45 or older with cataracts in both eyes, have had prior myopic (nearsighted) refractive surgery, and have regular corneal astigmatism (a common vision problem) of 0.6 D or less. The study will measure success by checking your binocular (using both eyes) corrected distance visual acuity (how well you see with glasses or contacts) three months after surgery. The current recruitment status is unclear.

Study design
This is an observational study with 40 participants, meaning researchers will observe outcomes without assigning different treatments. It is a single-center, single-arm study, so all participants will receive the same intervention.
What's involved
You would have assessments before surgery, and then again at 1 and 3 months after surgery. These assessments include questionnaires, eye exams, and measurements of your vision.
Compensation
Not stated in the trial record.
Follow-up
You will be followed for three months after your surgery to measure your visual acuity.

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NCT06555289

Outcomes of Clareon PanOptix Pro in Patients With Prior Myopic Refractive Surgery

Recruiting
Not specifiedAges 45+Observational
Juliette Eye Institute Research Center
~40 participants
Updated 2025-12-12 on ClinicalTrials.gov
What's tested:Clareon PanOptix Pro IOL

At a glance

Recruiting sites
1 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Binocular corrected distance visual acuity (logMAR)
Measured over 3 months postoperative
Cataract
1 sites across 1 states
New Mexico1
  • Robert Melendez, MD, MBA · PRINCIPAL_INVESTIGATOR · Juliette Eye Institute Research Center

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Eligibility criteria

Inclusion

Adults (45 years or older) who have confirmed age-related cataracts and are eligible for bilateral cataract surgery.
Prior binocular myopic photorefractive keratectomy (PRK) or myopic LASIK.
Patients who have regular corneal astigmatism less than or equal to 0.6 D and are candidates for the PanOptix Pro spherical IOL.
Patients who have regular corneal astigmatism and are candidates for PanOptix Pro toric IOL T3
Postoperative visual potential of monocular 20/25 or better, in the surgeon's judgement.

Exclusion

Any ocular comorbidity that might hamper postoperative visual acuity:
Corneal abnormality including corneal dystrophy, irregularity, and degeneration.
Moderate or severe dry eyes that can't be relieved after treatment.
History of or current anterior and posterior inflammation of any etiology.
Retinal pathology such as AMD, diabetic retinopathy, vein occlusion, etc.
Glaucoma of any kind.
Pregnancy or lactation.
Any ocular surgery other than corneal myopic refractive surgery (LASIK and PRK).
Patients with physical or intellectual disability (e.g. Down's Syndrome, Parkinson's Disease, unable to fixate)
Apple Kappa/chord mu ≥ 0.6.
Higher order corneal aberrations at pupil diameter of 4mm: \> 0.6 total RMS, \> 0.3 coma, \> 0.3 trefoil (to exclude irregular corneas)
Any patient requiring a limbal relaxing incision.
  • Binocular corrected distance visual acuity (logMAR)3 months postoperative