Neurofeedback Enhanced Cognitive Reappraisal Training for Anxiety
This study is looking at how a technique called neurofeedback, which helps you learn to control your brain activity, affects emotion regulation in young adults with anxiety. Researchers are testing two approaches: fMRI with Veritable-NF and fMRI with Sham-NF. They want to see if receiving feedback about your own brain activity can improve your ability to manage emotions. The study is open to young adults aged 18 to 24 who have a primary diagnosis of generalized anxiety disorder, social anxiety disorder, panic disorder, or illness anxiety disorder. Success in this study would mean seeing changes in brain activity (specifically in the prefrontal cortex, or PFC) and in how negative images are rated. The current recruitment status is unclear.
- Study design
- This interventional study plans to enroll 110 participants. It compares two different neurofeedback approaches.
- What's involved
- You would complete 4 visits, some of which can be done virtually. These visits include a clinical interview, questionnaires, and a practice session, and possibly a mock scan.
- Compensation
- Not stated in the trial record.
- Follow-up
- The primary outcomes are measured at approximately 60 minutes, which suggests a short follow-up period during the study visits.
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Neurofeedback Enhanced Cognitive Reappraisal Training - Phase 4
At a glance
Conditions
Where it's being run
1 sites across 1 statesStudy leadership
- Stefanie Russman Block, Ph.D · PRINCIPAL_INVESTIGATOR · University of Michigan
Who to contact
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Do you actually qualify for this trial?
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Inclusion
Exclusion
What this trial measures
- Change in prefrontal cortex (PFC) activity (baseline to transfer run) from the reappraise > look contrastApproximately 60 minutes
- Change in negative affect ratings of images from the International Affective Picture System (IAPS)Approximately 60 minutes
The Self-Assessment Manikin (SAM) is a pictorial assessment technique in which a changing manikin figure depicts values along the primary dimension of affective valence (positive/negative). Users may indicate emotional reactions along a scale from 1-9, with higher numbers indicating greater negative affect. After the scan, participants will rate each image they saw from the IAPS along this scale. Differences in SAM ratings from look to reappraise trials will be evaluated and compared between sham-NF and veritable-NF groups.