A Study of Hemodynamic Cardiopulmonary Exercise for Congenital Heart Disease
This study is looking at people with Congenital Heart Disease (a heart condition present at birth) who are already scheduled to have a Cardiac Catheterization (a procedure where a thin tube is inserted into a blood vessel to reach the heart). During this procedure, an additional test called invasive Cardiopulmonary Exercise Testing (CPET) will be performed. The main goal is to see how well these tests, done both at rest and during exercise, can find problems with blood flow in the heart. Researchers also want to compare these invasive tests to non-invasive (Doppler-derived) tests and understand how they relate to the severity of your heart condition. You can join if you are 18 or older, have Congenital Heart Disease, and are already having a clinically necessary Cardiac Catheterization. The study aims to enroll 200 participants.
- Study design
- This is an interventional study, meaning participants will receive a specific intervention. It plans to enroll 200 participants.
- What's involved
- You will undergo a standard Cardiac Catheterization, and during this procedure, invasive Cardiopulmonary Exercise Testing (CPET) will also be performed.
- Compensation
- Not stated in the trial record.
- Follow-up
- The primary measurements will be taken at Baseline (during the procedure).
AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.
A Study of Hemodynamic Cardiopulmonary Exercise for CHD
At a glance
Conditions
NCT06566196
Where you'd take part
This study runs at 1 site. They're the same protocol — you choose where, and that choice sets who your contact draft is addressed to.
Mayo Clinic
Rochester, Minnesotano site contact published
Recruiting
Sites open and close at different times, so the status above is per site — it can differ from the study's overall status.
Study leadership
- Alexander Egbe, M.B.B.S., M.P.H. · PRINCIPAL_INVESTIGATOR · Mayo Clinic
Who to contact
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Inclusion
Exclusion
What this trial measures
- Change in left ventricular end-systolic elastance from rest to peak exerciseBaseline
Change in left ventricular end-systolic elastance will be measured in ΔmmHg/mL
- Change in Left ventricular cardiac output from rest to peak exerciseBaseline
Change in left ventricular cardiac output will be measured in ΔL/min
- Change in systemic vascular resistance from rest to peak exerciseBaseline
Change in systemic vascular resistance will be measured in ΔWoods Units
- Change in right ventricular free-wall strain from rest to peak exerciseBaseline
Change in right ventricular free-wall strain will be measured in Δ%
- Change in right ventricular cardiac output from rest to peak exerciseBaseline
Change in right ventricular cardiac output will be measured in ΔL/min
- Change in pulmonary vascular resistance from rest to peak exerciseBaseline
Change in pulmonary vascular resistance will be measured in ΔWoods Units