NCT06567691

Endoscopic Gastroenterostomy Versus Surgical Gastrojejunostomy

Enrolling by Invitation
NAAges 18+InterventionalSupportive care
Vanderbilt University Medical Center
~34 participants
Updated 2025-08-26 on ClinicalTrials.gov
What's tested:EUS GastrojejunostomySurgical GastrojejunostomyGastric Outlet Obstruction Scoring System (GOOSS)

At a glance

Recruiting sites
0 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Compare of restoration of oral intake following EUS versus surgical gastrojejunostomy
Measured over 1 day post-operative
+1 more outcome measured
Malignant Gastric Outlet Obstruction
1 sites across 1 states
Tennessee1
  • Patrick Yachimski, MD · PRINCIPAL_INVESTIGATOR · Vanderbilt University Medical Center

This trial hasn't published a contact. View it on ClinicalTrials.gov

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Eligibility criteria

Inclusion

Age 18 years or older
Able to provide informed consent
Biopsy-proven cancer
Cancer without surgical resection as a curative treatment option
Clinical and radiographic presentation consistent with primary or metastatic tumor causing foregut obstruction at the level of the pylorus and/or duodenum

Exclusion

Age \<18 years
Pregnancy
Unable to provide informed consent
White Blood Count \< 3,000
Absolute Neutrophil Count \< 1,500
International normalized ratio \> 1.6
Platelet count \< 100,000
Cancer with surgical resection as a curative treatment option
Surgically altered foregut anatomy
Multifocal intestinal obstruction
Abdominal ascites prohibitive of surgical candidacy
Abdominal wall mesh prohibitive of surgical candidacy
Child's Class B or C cirrhosis
Gastroesophageal varices or known portal hypertension
Body mass index \>40
  • Compare of restoration of oral intake following EUS versus surgical gastrojejunostomy1 day post-operative

    A GOOSS score of 0 will be defined as intolerant of oral intake, while any GOOSS score greater than 0 will be defined as tolerant of oral intake. 0: no oral intake 1. oral liquids only 2. soft solids 3. low residue or full diet This will be given to subjects

  • Compare post procedure length of hospital stay14 days post-operative

    This outcome will be measured as the length of hospital stay (in days) from study intervention to discharge. Any accrued hospital stay from admission prior to study intervention will not be included in this assessment.