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Genetic Testing for Cancer Prevention in Indigenous American Communities (JUNIPER Trial)

This study, called the JUNIPER Trial, is looking at genetic changes in cells linked to different types of cancer in Indigenous American (IA) communities in the Southwest. The goal is to improve how cancer is found early, how it's prevented, and how it's treated for people in these communities. You may be able to join if you are an adult (18 or older) who identifies as Indigenous American and has cancer or is a cancer survivor. The study involves collecting blood or saliva samples and leftover tissue for genetic testing, and you will receive care plan recommendations. Researchers want to successfully enroll Indigenous American participants and return valuable genetic results to them within five years. The current status of this study is unclear.

Study design
This interventional study plans to enroll 300 participants. It is not specified if it is randomized or blinded.
What's involved
You would provide blood or saliva samples and leftover tissue samples, undergo genetic testing, and complete surveys. You would also receive care plan recommendations.
Compensation
Not stated in the trial record.
Follow-up
The study aims to return genetic results to participants for up to 5 years.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.

NCT06569316

Genetic Testing for the Prevention of Cancer in American Indian Communities (JUNIPER Trial)

Recruiting
NAAges 18+InterventionalScreening
Mayo Clinic
~300 participants
Updated 2026-07-29 on ClinicalTrials.gov
What's tested:Biospecimen CollectionCommunication InterventionGenetic TestingSurvey Administration

At a glance

Recruiting sites
1 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Successful accrual of American Indian (AI) participants
Measured over Up to 5 years
+1 more outcome measured

Conditions

Hematopoietic and Lymphatic System Neoplasm
Malignant Solid Neoplasm

Explore related trials

Hematologic NeoplasmSolid Neoplasm

NCT06569316

Where you'd take part

This study runs at 1 site. They're the same protocol — you choose where, and that choice sets who your contact draft is addressed to.

  • Mayo Clinic in Arizona

    Scottsdale, Arizonastudy coordinator listed

    Recruiting

Sites open and close at different times, so the status above is per site — it can differ from the study's overall status.

Study leadership

  • Jewel Samadder, MD · PRINCIPAL_INVESTIGATOR · Mayo Clinic

Who to contact

Clinical Trials Referral Office
[email protected]
855-776-0015
Email the study team

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Eligibility criteria

Inclusion

Male or female adults \>= 18 years of age
Cancer patient undergoing active treatment or a cancer survivor
Self-identify as American Indian

Exclusion

Unable to provide informed consent
Individuals who are under 18 years of age
Prisoners

What this trial measures

  • Successful accrual of American Indian (AI) participantsUp to 5 years

    Assessed by the number of AI participants consented to study.

  • Return of valuable genetic results to participantsUp to 5 years

    Assessed by the number of participants who receive genetic results. Clinically useful genomic data will be returned to participants with navigation to counseling and clinical resources as warranted and as they select.