Observational Study of Home-Based Monitoring in Parkinson's Disease
This study is looking at how well automated tools can help detect problems related to Parkinson's disease (PD) and predict how the disease might progress over one year. Researchers will use speech analysis, activity trackers worn at home, and smartphone video to measure things like fine motor skills and tremor. You might be able to join if you are between 50 and 110 years old and have been newly referred to the UIHC Movement Disorders Clinic for a possible Parkinson's disease evaluation. The study aims to see if these home-based measurements can improve our understanding of PD and its progression.
- Study design
- This is an observational study planning to enroll 120 participants. It will involve two groups: people newly referred for possible Parkinson's disease and people recently diagnosed with Parkinson's disease.
- What's involved
- You would attend a short research visit at the University of Iowa, make video and audio recordings, and wear an activity tracker at home for four weeks. A video visit will be conducted after four weeks to repeat some tasks.
- Compensation
- Not stated in the trial record.
- Follow-up
- Your fine motor function and total cognition composite function will be measured at baseline and again at one year.
AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.
Home-Based Monitoring in Parkinson's Disease
At a glance
Conditions
NCT06573762
Where you'd take part
This study runs at 1 site. They're the same protocol — you choose where, and that choice sets who your contact draft is addressed to.
University of Iowa Hospitals and Clinics
Iowa City, Iowastudy coordinator listed
Recruiting
Sites open and close at different times, so the status above is per site — it can differ from the study's overall status.
Study leadership
- Jacob Simmering, PhD · PRINCIPAL_INVESTIGATOR · University of Iowa
Who to contact
Opens a ready-to-send draft in your own email app — review before sending.
What this trial measures
- Number of Patients with a Diagnosis of Parkinson's DiseaseBaseline
Among Group 1 (those newly referred to the clinic for possible Parkinson's disease), a primary outcome will be whether the diagnosis made by the provider in the clinic was Parkinson's disease versus any other diagnosis. This is not an outcome for Group 2 (those with a recent diagnosis of Parkinson's disease) as everyone in that group will have that diagnosis.
- Change in Fine Motor FunctionBaseline, One Year
Motor function will be evaluated using the UPDRS rating system.
- Change in Total Cognition Composite FunctionBaseline, One Year
Total Cognition Composite will be calculated using the NIH Toolbox Cognition Battery. This score has a range from 0 to 200 with healthy adults having a mean score of 100 with a standard deviation of 15. Higher scores are associated with better cognitive performance.
- Change in Total Crystallized Cognition FunctionBaseline, One Year
Crystallized Cognition Composite will be calculated using the NIH Toolbox Cognition Battery. This score has a range from 0 to 200 with healthy adults having a mean score of 100 with a standard deviation of 15. Higher scores are associated with better cognitive performance.
- Change in Total Fluid Cognition FunctionBaseline, One Year
Fluid Cognition Composite will be calculated using the NIH Toolbox Cognition Battery. This score has a range from 0 to 200 with healthy adults having a mean score of 100 with a standard deviation of 15. Higher scores are associated with better cognitive performance.
- Change in Montreal Cognitive Assessment ScoresBaseline, One Year
The Montreal Cognitive Assessment (MoCA) has a range of 0-30. Higher scores are associated with better cognitive function. Scores of 26 or higher are considered cognitively normal. Scores less than 26 are suggestive of cognitive impairment, with dementia scores being below 20 but without a universally-accepted cutoff.