Cannabidiol for Cannabis Concentrate Users
This study is looking at whether Broad Spectrum Cannabidiol (bsCBD) can help people who regularly use cannabis concentrates. You might be able to join if you are between 25 and 60 years old, use cannabis concentrates at least four times a week, and are not currently trying to stop or cut down your use. You also need to have been able to stop using cannabis for three days in a row in the last 90 days without severe withdrawal symptoms. Participants will take either 200 mg or 400 mg of bsCBD, or a placebo (an inactive substance), by mouth daily for four weeks. The researchers will measure levels of THC (delta-9-tetrahydrocannabinol) and THC-COOH (11-Nor-9-carboxy-THC) in your blood, and also track your cannabis use, to see if bsCBD reduces how much cannabis concentrate you use.
- Study design
- This is a randomized, placebo-controlled study with 120 planned participants. Participants will be assigned by chance to one of three groups: 200 mg bsCBD, 400 mg bsCBD, or placebo.
- What's involved
- You will take medication by mouth with food daily for four weeks. You will also complete three visits in a mobile laboratory during this period.
- Compensation
- Not stated in the trial record.
- Follow-up
- The main measurements for the study are taken at 4 weeks.
AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.
Cannabidiol and Cannabis Concentrate Users
At a glance
Conditions
Where it's being run
1 sites across 1 statesStudy leadership
- Joseph P Schacht, PhD · PRINCIPAL_INVESTIGATOR · University of Colorado, Denver
Who to contact
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What this trial measures
- Difference in blood 11-Nor-9-carboxy-THC (THC-COOH) levels4 weeks
THC-COOH levels in blood samples collected at baseline, Week 2, and Week 4 of medication ingestion
- Difference in blood delta-9-tetrahydrocannabinol (THC) levels4 weeks
THC levels in blood samples collected before and after cannabis use at baseline and at Week 4 of medication ingestion
- Difference in cannabis use4 weeks
Total number of days of cannabis use during the 4-week medication period as reported on daily diaries