Optimizing Pain Control After Tonsillectomy in Children and Adolescents
This study is looking at ways to improve pain control after tonsillectomy (surgery to remove tonsils) in children and adolescents aged 3 to 17. Researchers are comparing two types of pain medication given during surgery: methadone, a long-acting opioid, versus fentanyl or hydromorphone, which are shorter-acting opioids given as needed. The main goal is to see if methadone can reduce the need for additional pain medication in the recovery room after surgery. You might be eligible if you are having an elective tonsillectomy and meet other health criteria. The study aims to enroll 440 participants, but its current status is unclear.
- Study design
- This is a randomized, double-blind study where participants are assigned to either methadone or short-acting opioids, with 440 participants planned.
- What's involved
- You would have outcomes data collected in the hospital, daily surveys for 7 days after discharge, and three phone calls at 30 days, 3 months, and 6 months after surgery.
- Compensation
- Not stated in the trial record.
- Follow-up
- Participants will be followed for 6 months after surgery.
AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.
Optimization of Pediatric Tonsillectomy to IMprove AnaLgesia
At a glance
Conditions
Where it's being run
1 sites across 1 statesStudy leadership
- Lisa M. Einhorn, MD · PRINCIPAL_INVESTIGATOR · Duke University
Who to contact
Opens a ready-to-send draft in your own email app — review before sending.
What this trial measures
- Number of participants who required rescue opioid administration in the PACU (post-anesthesia care unit)Up to 6 hours post surgery
Binary (yes/no) need for opioid in the PACU