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NCT06577714

Ablation Guided Via Precision Imaging Using Electromechanical Wave Imaging

Enrolling by Invitation
NAAges 18+InterventionalTreatment
Columbia University
~322 participants
Updated 2026-04-27 on ClinicalTrials.gov
What's tested:Electromechanical wave imaging (EWI)

At a glance

Recruiting sites
0 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Proportions of correct predictions for location of arrhythmia in both standard of care ECG reads compared to EWI maps
Measured over Up to 1 week
+1 more outcome measured

Conditions

Arrhythmias, Cardiac

Explore related trials

ArrhythmiaAtrial FlutterAtrial Premature Complex by ECG FindingAtrial TachycardiaVentricular premature complexWolff-Parkinson-White Syndrome

Where it's being run

1 sites across 1 states
New York1

Who to contact

This trial hasn't published a contact. View it on ClinicalTrials.gov

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Eligibility criteria

Inclusion

\>=18 years of age
Able to give consent for the study
Scheduled for Invasive Electrophysiology Study (EPS) +/- ablation for atrial tachycardia (AT), atrial flutter (AFL), Wolff-Parkinson-White syndrome (WPW) or premature atrial complexes/premature ventricular complexes (PAC/PVCs)

Exclusion

Patient is not in clinical arrhythmia at the time of scan despite leg lifts, or intravenous isoproterenol/dobutamine infusion
Patient is not able to comply with study protocol due to cognitive impairment, severe mental illness, or planned moved during the study period
Treating physician does not agree with enrollment
Patient does not speak English or Spanish
Pregnancy

What this trial measures

  • Proportions of correct predictions for location of arrhythmia in both standard of care ECG reads compared to EWI mapsUp to 1 week

    A correct prediction is defined as if it correctly identifies the location of the arrhythmia. A correct prediction is defined as if it correctly identifies the location of the arrhythmia. The 3D EWI maps will be generated prior to procedure and acquisition of the image takes usually takes 15 minutes. Data processing will take at least 1-3 days and will be available prior to the start of the electrophysiology study. Comparative analysis of the results from 3D EWI to the 3D high density electroanatomical maps will take place up to 1 week after the procedure to compare the prediction of target ablation to the area of ablation success.

  • Proportions of correct predictions for mechanism of arrhythmia in both standard of care ECG reads compared to EWI mapsUp to 1 week

    A correct prediction is defined as 1) a method correctly identifies an arrhythmia as focal or macro-reentrant The 3D EWI maps will be generated prior to procedure and acquisition of the image takes usually takes 15 minutes. Data processing will take at least 1-3 days and will be available prior to the start of the electrophysiology study. Comparative analysis of the results from 3D EWI to the 3D high density electroanatomical maps will take place up to 1 week after the procedure to compare the predicted mechanism to the invasively acquired activation map revealing the true mechanism of the arrhythmia