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NCT06585605

A Retrospective Survey-based Multicenter Study to Delineate the Molecular and Phenotypic Spectrum of Epilepsy-dyskinesia Syndromes

Recruiting
Not specifiedAges 0–18Observational
Boston Children's Hospital
~500 participants
Updated 2026-03-18 on ClinicalTrials.gov

At a glance

Recruiting sites
1 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Creation of a Shared Clinical Database
Measured over 1 year
+3 more outcomes measured

Conditions

Epilepsy in Children
Dyskinesias
Movement Disorders in Children
Neurologic Disorder
Chorea
Myoclonus
Ataxia
Epilepsy
Dystonia Disorder
Movement Disorders

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NCT06585605

Where you'd take part

This study runs at 1 site. They're the same protocol — you choose where, and that choice sets who your contact draft is addressed to.

  • Boston Children's Hospital

    Boston, Massachusettsstudy coordinator listed

    Recruiting

Sites open and close at different times, so the status above is per site — it can differ from the study's overall status.

Who to contact

Darius Ebrahimi-Fakhari, MD, PhD.
[email protected]
617-355-0097
Email the study team

Opens a ready-to-send draft in your own email app — review before sending.

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Add a private profile and we'll compare every criterion below against your situation — and tell you which ones are met, uncertain, or excluding.

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Eligibility criteria

Inclusion

Children between 0 - 18 years of age with a movement disorder and a pathogenic or likely pathogenic variant in one of the genes of interest:

Exclusion

Not having such diagnosis and/or not presenting a movement disorder.

What this trial measures

  • Creation of a Shared Clinical Database1 year

    The primary endpoint of this multi-center study will be the creation of the Epilepsy-Dyskinesia Study and the enrollment of 350 individuals in a shared database.

  • Understanding of Disease Spectrum1 year

    To comprehensively understand the spectrum and association of movement and seizure disorders on both clinical and molecular levels.

  • Assess the Impact of Movement Disorders on Health-Related Quality of Life1 year

    To assess the impact of movement disorders on health-related quality of life specifically within the context of epilepsy-dyskinesia syndromes.

  • Investigate the Efficacy of Symptomatic Treatments1 year

    Investigate the efficacy of symptomatic treatments in addressing both seizure and movement disorders, aiming to identify shared therapeutic strategies.