The SWAP-9 Study: Comparing Antiplatelet Strategies After Stent Placement

This study, called SWAP-9, is looking at different ways to manage antiplatelet medicines after you've had a stent placed for coronary artery disease (CAD). Specifically, it's comparing two approaches: continuing with strong antiplatelet medicines like prasugrel or ticagrelor, or switching to a combination of aspirin and clopidogrel. The goal is to see how these different strategies affect your body's antiplatelet response. You might be able to join if you've had a stent and are currently taking aspirin along with prasugrel or ticagrelor. The study will measure how well your blood platelets are being controlled after about 30 days.

Study design
This interventional study plans to enroll 90 participants. It compares two different antiplatelet treatment strategies.
What's involved
Not specified in the trial record.
Compensation
Not stated in the trial record.
Follow-up
Your platelet response will be measured at 30 ± 5 days after starting the new treatment strategy.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.

NCT06588595

The Switching Antiplatelet-9 (SWAP-9) Study

Recruiting
PHASE4Ages 18+InterventionalTreatment
University of Florida
~90 participants
Updated 2026-02-25 on ClinicalTrials.gov
What's tested:Prasugrel/Ticagrelor monotherapy or aspirin plus clopidogrelAspirin plus clopidogrel

At a glance

Recruiting sites
1 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
P2Y12 Reaction Units (PRU)
Measured over At 30±5 days (trough levels)
Coronary Arterial Disease (CAD)
1 sites across 1 states
Florida1

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  • P2Y12 Reaction Units (PRU)At 30±5 days (trough levels)

    Comparison of PRU determined by VerifyNow between ABCD-GENE-guided de-escalation vs. unguided de-escalation.