Study for Opioid Use Disorder After Emergency Department Discharge

This study is testing a 'bundled intervention' for people with opioid use disorder (OUD) who have recently been discharged from the emergency department (ED) after an opioid overdose. The intervention includes peer support, buprenorphine (a medication for OUD), telehealth (medical care through technology), and community addiction programs. You could join if you are 19 or older, have been diagnosed with OUD, had an opioid overdose in the last year, were prescribed buprenorphine in the ED, and are willing to continue it. The study aims to see if this bundled approach helps people stay in treatment and connected to addiction programs. The current recruitment status is unclear, and the study plans to enroll 190 participants.

Study design
This is an interventional study comparing a bundled intervention to usual care, with a planned enrollment of 190 participants.
What's involved
Not specified in the trial record.
Compensation
Not stated in the trial record.
Follow-up
Participants will be followed for 1 month and 3 months after ED discharge to check retention, buprenorphine adherence, and linkage to treatment programs.

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NCT06593093

A Bundled Intervention

Recruiting
PHASE1Ages 19+InterventionalTreatment
University of Alabama at Birmingham
~190 participants
Updated 2026-02-23 on ClinicalTrials.gov
What's tested:a bundled interventioncontrol group

At a glance

Recruiting sites
1 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
participant retention rate
Measured over 1 month and 3 months post ED discharge
+2 more outcomes measured
Opioid Use Disorder
Opioid Overdose
1 sites across 1 states
Alabama1
  • Li Li, MD;PhD · PRINCIPAL_INVESTIGATOR · University of Alabama at Birmingham

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  • participant retention rate1 month and 3 months post ED discharge

    measure the total number of participants who complete 1- month and 3-month treatment in the study

  • buprenorphine adherent rate1 month and 3 months post ED discharge

    checking prescription rate and patients' report of their taking medication rate

  • linkage rate to addiction treatment programs1 month and 3 months post ED discharge

    patients' self report and reports from addiction treatment programs