NCT06594705

The JenaValve ALIGN-AR LVAD Registry

Active, Not Recruiting
NAAges 18+InterventionalTreatment
JenaValve Technology, Inc.
~50 participants
Updated 2026-07-22 on ClinicalTrials.gov
What's tested:JenaValve Trilogy Heart Valve System

At a glance

Recruiting sites
0 of 14 listed sites are recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Device Success
Measured over 30 days
+10 more outcomes measured
Aortic Regurgitation
Aortic Valve Insufficiency
Aortic Insufficiency
Aortic Valve Disease
Left Ventricular Dysfunction
14 sites across 11 states
California2
Michigan2
Texas2
District of Columbia1
Georgia1
Illinois1
Minnesota1
Missouri1
  • Nir Uriel, MD · STUDY_CHAIR · Columbia University
  • Vinod Thourani, MD · PRINCIPAL_INVESTIGATOR · Piedmont Heart Institute
  • Ravi Ramana, DO · PRINCIPAL_INVESTIGATOR · advocate christ medical center
  • Gabriel Sayer, MD · PRINCIPAL_INVESTIGATOR · Columbia University

This trial hasn't published a contact. View it on ClinicalTrials.gov

  • Device Success30 days

    Freedom from unsuccessful delivery of the device, and retrieval of the delivery system

  • Device Positioning30 days

    Freedom from incorrect positioning of a single prosthetic heart valve into the proper anatomical location

  • Device Performance30 days

    Intended performance of the valve (i.e., no moderate or severe prosthetic valve regurgitation)\*

  • Surgery/intervention related to device30 days

    Freedom from surgery or intervention related to the device# or to a major vascular or access-related or cardiac structural complication

  • Bleeding30 days

    Freedom from VARC type 2-4 bleeding

  • All Stroke30 days

    Number of patients that had stroke

  • Acute Kidney Injury30 days

    Number of patients that had acute kidney injury (AKI) stage 3 or 4

  • Total aortic regurgitation30 days

    Number of patients that had moderate or severe total aortic regurgitation

  • Major Vascular Complication30 days

    Number of patients that had major vascular, access-related, or cardiac structural complication

  • Permanent pacemaker implantation30 days

    Number of patients that had these events

  • All-cause mortality30 days

    All-cause mortality within the first 30 days post index procedure