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Study on Nicotine Pouch Characteristics and Perceptions

This study is looking at how different features of nicotine pouches, like nicotine strength and pH level, affect how people perceive and use them. You might be able to join if you are between 21 and 35 years old, currently use nicotine pouches (and may also use e-cigarettes or regular cigarettes), and are not planning to quit nicotine. You'll need to pass a cotinine test (a test for nicotine in your saliva). The study aims to understand what makes nicotine pouches appealing and how people experience them. There are 72 participants planned for this study.

Study design
This is a single-visit, double-blind (meaning neither you nor the researchers will know which pouch you're using) randomized study involving 72 participants.
What's involved
You will attend an orientation session, then a single 4-hour experimental session where you will self-administer four different nicotine pouches. You'll need to avoid nicotine for 8 hours before the experimental session.
Compensation
Not stated in the trial record.
Follow-up
Your perceptions and sensory experiences will be measured during the 3-hour experimental session while you use the pouches.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.

NCT06597435

Effects of Nicotine Pouch Characteristics on Perceptions and Behavior

Recruiting
NAAges 21–35Interventional
University of Southern California
~72 participants
Updated 2024-12-06 on ClinicalTrials.gov
What's tested:Nicotine pouch

At a glance

Recruiting sites
1 of 2 listed sites are recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Subjective Appeal and sensory experience
Measured over During the 3-hour experimental session, participant will self-administer 4 nicotine pouches, each with a 5-minute administration period. There will a 40-minute inter-product rest interval.

Conditions

Nicotine Pouch Self-Administration

Explore related trials

Nicotine Pouch Self-AdministrationCotinine

Where it's being run

2 sites across 1 states
California2

Study leadership

  • Dae Hee Han, PhD · PRINCIPAL_INVESTIGATOR · University of Southern California

Who to contact

Dae Hee Han, PhD
[email protected]
626-200-8334
Email the study team

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Do you actually qualify for this trial?

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Eligibility criteria

Inclusion

Adults age 21-35 years old.
Current nicotine pouch users (used nicotine pouches in the past 30 days). Current dual users of nicotine pouches and e-cigarettes and/or combustible cigarettes will be eligible.
Positive cotinine test via saliva test strip.
Unmotivated to quit nicotine use.
English language competency (read and speak English). The instruments used have not been translated and/or validated for other languages.

Exclusion

Intention to quit nicotine use in the next 30 days.
Current pregnancy or breastfeeding (urine pregnancy test will be conducted during the orientation session).
History of stroke, seizures, high blood pressure (hypertension), heart disease/problems, lung disease/lung problems, or cardiovascular disease contraindications for nicotine.
People under 21 years will be excluded to correspond with the legal age for purchasing tobacco products in the United States. Special subject populations will not be recruited.

What this trial measures

  • Subjective Appeal and sensory experienceDuring the 3-hour experimental session, participant will self-administer 4 nicotine pouches, each with a 5-minute administration period. There will a 40-minute inter-product rest interval.

    Self-report measures of product appeal (e.g., liking, disliking, willingness to use again) and sensory attributes (e.g., sweetness, smoothness, bitterness, harshness) will be completed following the nicotine pouch administration.