MAMA Tot - Healthy Weight Parallel Study for Pregnant Women

This study is looking at how different types of exercise during pregnancy affect the health of both mothers and their babies. Researchers want to see if moderate intensity aerobic exercise, resistance exercise, or a combination of both can improve heart and metabolic health in infants. You might be able to join if you are a woman between 18 and 40 years old, have a healthy body mass index (BMI between 18.5 and 24.4), are pregnant with one baby (16 weeks gestation or less), and your doctor says exercise is okay. The main goal is to measure infant non-HDL cholesterol (a type of fat in the blood) at 1, 6, and 12 months after birth to see which exercise type has the biggest impact. The study plans to enroll 268 healthy pregnant women.

Study design
This is a randomized controlled trial involving 268 healthy pregnant women. Participants will be assigned to an exercise group (aerobic, resistance, or combined) or a usual care group (no exercise).
What's involved
Not specified in the trial record.
Compensation
Not stated in the trial record.
Follow-up
Infants will be measured at 1, 6, and 12 months of age after birth.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.

NCT06598098

MAMA Tot - Healthy Weight Parallel Study

Recruiting
NAAges 18–40InterventionalPrevention
East Carolina University
~268 participants
Updated 2024-09-19 on ClinicalTrials.gov
What's tested:Exercise Modes

At a glance

Recruiting sites
1 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
1 month Infant non-HDL
Measured over 1 month
+11 more outcomes measured
Pregnancy Related
1 sites across 1 states
North Carolina1
  • Linda May, MS, PhD · PRINCIPAL_INVESTIGATOR · East Carolina University

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Eligibility criteria

Inclusion

Age: 18 to 40 years old
BMI 18.5 to 24.4
Pregnancy: Singleton; ≤ 16 weeks gestation
Clearance by Obstetric provider for exercise

Exclusion

Age: ≤ 17.9 or ≥ 41 years of age
BMI ≥25
Multi fetal pregnancy
Obstetric Provider does not provide clearance for exercise
Unable or Unwilling to provide consent
Inability to communicate with members of study team, despite use of interpreter
Medical Conditions (e,g. HIV/Aids, Cancer, Type 1 or 2 Diabetes, Untreated Hypertension, Thyroid Disorders)
Use of tobacco products, alcohol, recreational drugs, or medications (oral hypertensive, insulin)
Unable to provide phone or email contact
  • 1 month Infant non-HDL1 month

    non-HDL measures from venipuncture

  • 6 month Infant non-HDL6 months

    non-HDL measures from venipuncture

  • 12 month Infant non-HDL12 months

    non-HDL measures from venipuncture

  • 1 month infant BMI z-score1 month

    BMI normalized

  • 6 month infant BMI z-score6 months

    BMI normalized

  • 12 month infant BMI z-score12 months

    BMI normalized

  • Enrollment (8-13wks) Maternal fasting non-HDLenrollment (~8-13 wks gestation)

    non-HDL measured from venipuncture

  • 36wk Maternal fasting non-HDL36wks gestation

    non-HDL measured from venipuncture

  • 1 month Maternal fasting non-HDL1 month postpartum

    non-HDL measured from venipuncture

  • 6 month Maternal fasting non-HDL6 months postpartum

    non-HDL measured from venipuncture

  • Adverse Pregnancy OutcomesAt delivery

    Presence or absence of Adverse Pregnancy outcomes (preterm birth, gestational diabetes \[GDM\], preeclampsia, hypertension)

  • 12 month Maternal fasting non-HDL12 months postpartum

    non-HDL measured from venipuncture