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Behavioral Intervention for Lifestyle Physical Activity in Parkinson's Disease

This study is testing a 16-week program called GET Up PD, which combines aerobic exercise (like walking) and resistance training, against a stretching and flexibility program. Both programs are delivered remotely. The goal is to see if GET Up PD can increase your physical activity and improve thinking skills, symptoms, and quality of life if you have Parkinson's disease (PD). You might be able to join if you have a confirmed diagnosis of PD, are between 50 and older, have internet access, and are not currently very physically active. The study will measure changes in how much light, moderate, and vigorous physical activity you do after 16 weeks. The current status of this study is unclear.

Study design
This is a randomized controlled trial planning to enroll 50 participants. You would be randomly assigned to either the GET Up PD exercise group or a stretching and flexibility group.
What's involved
You would complete cognitive assessments and questionnaires, wear an accelerometer (a device to measure movement), and participate in a 16-week program.
Compensation
Not stated in the trial record.
Follow-up
Your physical activity will be measured at the start of the study and again after 16 weeks (post-intervention).

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.

NCT06603012

Behavioral Intervention for Lifestyle Physical Activity in Parkinson's Disease

Not Yet Recruiting
NAAges 50+InterventionalTreatment
University of Illinois at Chicago
~50 participants
Updated 2026-06-04 on ClinicalTrials.gov
What's tested:GET Up PDStretching and Flexibility

At a glance

Recruiting sites
0 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Physical Activity
Measured over Changes in time spent in light physical activity from Baseline (pre-intervention) to after 16 weeks (post-intervention)
+1 more outcome measured

Conditions

Parkinson Disease (PD)

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NCT06603012

Where you'd take part

This study runs at 1 site. They're the same protocol — you choose where, and that choice sets who your contact draft is addressed to.

  • University of Illinois at Chicago

    Chicago, Illinoisstudy coordinator listed

Sites open and close at different times, so the status above is per site — it can differ from the study's overall status.

Study leadership

  • Robert Motl, PhD · PRINCIPAL_INVESTIGATOR · University of Illinois at Chicago

Who to contact

Brenda Jeng, PhD
[email protected]
312-996-6615
Email the study team

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Eligibility criteria

Inclusion

confirmed diagnosis of PD
Internet and email access
willingness to complete the cognitive assessments and questionnaires, wear the accelerometer, and undergo randomization
insufficient physical activity (i.e., not meeting current physical activity guidelines) based on a health contribution score of less than 14 units from the Godin Leisure-Time Exercise Questionnaire
self-reported ability to ambulate without assistance
age of 50+ years
English as a primary language
asymptomatic (i.e., one or fewer affirmatives on the Physical Activity Readiness Questionnaire \[PAR-Q\]) or physician approval for undertaking exercise training for those with 2 or more affirmatives on the PAR-Q
moderate or high risk of contraindications for possible injury or death when undertaking strenuous or maximal exercise using the PAR-Q
severe cognitive impairment that might preclude compliance with the conditions based on a modified Telephone Interview for Cognitive Status (TICS-M) score of less than 18
normal cognitive impairment based on the Montreal Cognitive Assessment (MoCA) score of 26 or more for avoiding ceiling effects involving change in cognitive function

What this trial measures

  • Physical ActivityChanges in time spent in light physical activity from Baseline (pre-intervention) to after 16 weeks (post-intervention)

    ActiGraph Gt3X+ accelerometer; minutes spent in light physical activity per day

  • Physical ActivityChanges in time spent in moderate-to-vigorous physical activity from Baseline (pre-intervention) to after 16 weeks (post-intervention)

    ActiGraph Gt3X+ accelerometer; minutes spent in moderate-to-vigorous physical activity per day