Observational Study on Antibodies and Cytokines in Chronic Granulomatous Disease
This study is looking at people with Chronic Granulomatous Disease (CGD) to understand more about their immune system. Researchers want to measure the levels of certain antibodies (proteins that fight infections) and cytokines (proteins that help control inflammation) in your blood. This will help them learn about how common these markers are in people with CGD. You could join if you have CGD, which means your doctor has confirmed that your white blood cells don't work properly (NADPH oxidase activity is ≤5% or you have a specific gene change). The study aims to find out the levels of total adenoviral-specific antibody (TAb) and adenoviral-specific neutralizing antibody (NAb) in your blood. This is an observational study, meaning researchers will collect information without giving you any new treatments. The study is currently unclear about its recruitment status and plans to include 60 participants.
- Study design
- This is an observational study that plans to include 60 participants. It is not a randomized or blinded study.
- What's involved
- Blood samples will be collected from you. The levels of certain antibodies and inflammatory cytokines will be measured from these samples.
- Compensation
- Not stated in the trial record.
- Follow-up
- The primary endpoints (antibody levels) are measured at 1 Day. It is not specified if there is follow-up beyond this.
AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.
Prevalence of Antibodies and Cytokines in Participants With Chronic Granulomatous Disease
At a glance
Conditions
NCT06605378
Where you'd take part
This study runs at 52 sites. They're the same protocol — you choose where, and that choice sets who your contact draft is addressed to.
Home-based telemedicine
Montgomery, Alabamastudy coordinator listed
Recruiting
Home-based telemedicine
Phoenix, Arizonastudy coordinator listed
Recruiting
Home-based telemedicine
Little Rock, Arkansasstudy coordinator listed
Recruiting
Home-based telemedicine
Sacramento, Californiastudy coordinator listed
Recruiting
Home-based telemedicine
Denver, Coloradostudy coordinator listed
Recruiting
Home-based telemedicine
Hartford, Connecticutstudy coordinator listed
Recruiting
Home-based telemedicine
Dover, Delawarestudy coordinator listed
Recruiting
Home-based telemedicine
Washington D.C., District of Columbiastudy coordinator listed
Recruiting
Sites open and close at different times, so the status above is per site — it can differ from the study's overall status.
Who to contact
Opens a ready-to-send draft in your own email app — review before sending.
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Inclusion
Exclusion
What this trial measures
- Total adenoviral-specific antibody (TAb) titer1 Day
Level of total adenoviral-specific antibody in blood
- Adenoviral-specific neutralizing antibody (NAb) titer1 Day
Level of adenoviral-specific neutralizing antibodies in blood