Observational Study for Cancer Detection and Recurrence Risk

This is an observational study for people with certain solid tumors, including muscle invasive bladder cancer, esophageal cancer, gastric cancer, melanoma (skin cancer), and non-small cell lung cancer. The study aims to collect clinical information, blood, and tumor tissue samples to help develop better tests for understanding cancer, such as improving detection and predicting if cancer might return. You would receive your usual standard of care from your doctor. The main goal is to create a registry of these samples. This study is open to adults aged 18 and older who have stage I, II, or operable stage III cancer and are planning to have surgery. The study's status is currently unclear.

Study design
This is an observational study with a planned enrollment of 1350 participants. The phase of the study is not specified.
What's involved
You would provide blood and tissue samples as part of your routine standard of care. Your involvement is expected to last for approximately five and a half (5.5) years.
Compensation
Not stated in the trial record.
Follow-up
Participants will be observed from enrollment up to 5.5 years after enrollment to collect blood and tissue biospecimens.

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NCT06605404

Pan-tumor MRD Study

Recruiting
Not specifiedAges 18+Observational
Paradigm Health
~1,350 participants
Updated 2025-08-14 on ClinicalTrials.gov
What's tested:blood and tissue samples

At a glance

Recruiting sites
2 of 2 listed sites are recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Blood and tissue biospecimen registry
Measured over Observation from enrollment to 5.5 years after enrollment
Muscle Invasive Bladder Urothelial Carcinoma
Esophageal Cancer
Gastric and Gastroesophageal Junction (GEJ) Adenocarcinoma
Melanoma (Skin Cancer)
NSCLC (Non-small Cell Lung Cancer)
Pancreatic (Exocrine Only)
Mix of Solid Tumors (MOST)
2 sites across 2 states
California1
Ohio1

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  • Blood and tissue biospecimen registryObservation from enrollment to 5.5 years after enrollment

    To establish a blood and tissue biospecimen resource in participants with operable solid tumors, with clinical, lab, radiographic, and pathology annotation for the discovery, development, and validation of MRD assays.