This study is looking at how a blood test, called circulating tumor DNA (ctDNA) testing, can help doctors understand if squamous cell carcinoma (a type of skin or head and neck cancer) might come back after treatment. Researchers will collect blood and tissue samples from about 250 participants who have squamous cell carcinoma of the head and neck or skin. You would be eligible if you are 18 or older and are planning to have standard treatment like surgery or radiation. The main goal is to see how often ctDNA is found in your blood within two years after your treatment. This information could help doctors better monitor patients for cancer relapse in the future.

Study design

This is an observational study, meaning researchers will watch and collect information without giving new treatments. It plans to include about 250 participants.

What's involved

You would provide blood samples before, during, and after your standard cancer treatment for up to two years. Tissue samples from your biopsy or surgery will also be collected at the start.

Compensation

Not stated in the trial record.

Follow-up

Participants will be followed for up to two years to measure ctDNA levels.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.