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Understanding Brain Stimulation and Reading

This study is looking at how different types of brain stimulation, called iTBS and cTBS, affect reading and language. Researchers want to understand how quickly, easily, and accurately people read after receiving these stimulations. They also want to find out how long the effects last and when they are strongest. You might be able to join if you are between 18 and 30 years old and have normal reading skills and at least low average intellectual functioning. The study will compare iTBS and cTBS to a 'sham' stimulation (which feels like real stimulation but doesn't actually affect the brain) to see how they impact your reading abilities. The goal is to enroll 50 participants.

Study design
This is an interventional study planning to enroll 50 participants. It will compare different types of brain stimulation (iTBS, cTBS, and sham stimulation) to see their effects.
What's involved
Not specified in the trial record.
Compensation
Not stated in the trial record.
Follow-up
Your reading speed will be measured at four time points: 20, 40, 60, and 80 minutes after each stimulation.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.

NCT06608680

Timing and Facilitation Effects of Theta-Burst Stimulation in the Reading and Language Networks

Recruiting
NAAges 18–30InterventionalBasic science
Georgia State University
~50 participants
Updated 2026-09-09 on ClinicalTrials.gov
What's tested:iTBScTBSSham Stimulation

At a glance

Recruiting sites
1 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Phonological Decoding Reaction Time
Measured over Four time points after each stimulation (20, 40, 60 and 80 minutes after stimulation)

Conditions

Reading
Language
Control Subjects

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Healthy Volunteers

NCT06608680

Where you'd take part

This study runs at 1 site. They're the same protocol — you choose where, and that choice sets who your contact draft is addressed to.

  • Georgia State University

    Atlanta, Georgiastudy coordinator listed

    Recruiting

Sites open and close at different times, so the status above is per site — it can differ from the study's overall status.

Who to contact

Rachael Harrington, Ph.D. CCC-SLP
[email protected]
404-413-6219
Email the study team

Opens a ready-to-send draft in your own email app — review before sending.

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Eligibility criteria

Inclusion

Subjects must have a minimum of low average intellectual functioning (\>=80) on at least one subscale on the Wechsler Abbreviated Scale of Intelligence-2 (WASI-2; Wechsler, 2011) to be included.
Within a normal range of reading skills as \>85 on the Test of Word Reading Efficiency - Second Edition (TOWRE-2; Torgesen et al., 2012) and the Woodcock-Johnson IV Tests of Achievement (WJ-IV; Schrank et al., 2014)
Individuals with a documented history of learning disability will not be included. This will be determined via demographics questionnaire.
Subjects must be between the ages of 18 and 30 to be included. This will be determined via demographics questionnaire.
Because reading is critically linked to language, only individuals who are native speakers of English will be included in the study. This will be determined via demographics questionnaire.
The reading network is typically localized to the left side of the brain. However, left-handed individuals may have different brain lateralization, introducing an important confound to the study. Therefore, only right-handed individuals will be included in the study. This will be determined via demographics questionnaire.
Individuals who have hearing deficits (\>25dB at 500+ Hz), visual deficits (\>20/40), serious emotional problems, certain neurological conditions (e.g., uncontrolled seizure disorders) will not be included. This will be determined via CABI Screening Forms and Demographics Questionnaire.
Individuals with certain metals in their bodies or with certain health conditions will not be included. If an individual has braces on their teeth, a cardiac pacemaker; hearing aid; other metal in their body or eyes (which may include certain metallic-embedded tattoos), including but not limited to pins, screws, shrapnel, plates, dentures or other metal objects they will not be included. This will be determined via CABI Screening forms.
Individuals with MRI Screening and Contraindication Forms which do not pass MRI Tech review will not be included.
Individuals with TMS Screening Forms which do not pass TMS Tech review will not be included.

What this trial measures

  • Phonological Decoding Reaction TimeFour time points after each stimulation (20, 40, 60 and 80 minutes after stimulation)