Computer-based Cognitive Training for Multiple Sclerosis

This study is testing a computer-based cognitive training program to see if it can help improve learning and memory in people with multiple sclerosis (MS). Cognitive (thinking) problems are common in MS and can affect daily life. The training involves 10 sessions over five weeks, delivered on a laptop via Zoom Health. You would either receive the "Learning and memory training" or "Sham Comparator" (placebo) exercises. Researchers will measure your learning and memory skills before and immediately after the training to see if it helps. To join, you need to be 19-65 years old, speak English, and have an MS diagnosis. You cannot have had a recent MS flare-up or other neurological conditions like a stroke.

Study design
This is an interventional study planning to enroll 40 participants. It compares a behavioral intervention (Learning and memory training) to a sham behavioral intervention (Sham Comparator).
What's involved
You would participate in 10 training sessions over five weeks, twice a week, using a laptop via Zoom Health. Your learning and memory will be assessed at the start and immediately after the training.
Compensation
Not stated in the trial record.
Follow-up
Your learning and memory will be assessed within one week after training completion.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.

NCT06608797

Testing the Feasibility of Computer-based Cognitive Training in Individuals with Multiple Sclerosis Living in the Community

Recruiting
NAAges 19–65InterventionalTreatment
Kessler Foundation
~40 participants
Updated 2025-02-21 on ClinicalTrials.gov
What's tested:Learning and memory trainingSham Comparator

At a glance

Recruiting sites
1 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
California Learning Verbal Test III
Measured over Primary outcome will be assessed at baseline (1 week before training start) and immediate follow-up (within 1 week after training completion)
Multiple Sclerosis
1 sites across 1 states
New Jersey1
Silvana L Costa Research Scientist, PhD
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Do you actually qualify for this trial?

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Eligibility criteria

Inclusion

English as primary language
Diagnosis of multiple sclerosis

Exclusion

Most recent exacerbation within one month
Other Neurological History: head injury, stroke, seizures, or any other significant neurological history will not be included in the study
Individuals with an active diagnosis of Major Depressive Disorder, Schizophrenia, Bipolar Disorder I or II will be excluded from the study.
Poor Visual Acuity (corrected vision in worse eye \< 20/60), diplopia, or nystagmus
Inability to understand directions and following one, two, and three step commands
Intact New Learning and Memory: Only individuals that show impaired performance on a memory test will be included in the study
  • California Learning Verbal Test IIIPrimary outcome will be assessed at baseline (1 week before training start) and immediate follow-up (within 1 week after training completion)