This study is looking at how different doses of THC (tetrahydrocannabinol), the main active compound in cannabis, affect how much people want to smoke cigarettes. Researchers will give participants either a high dose (30mg), a low dose (5mg), or a placebo (0mg) of THC. They will then measure how much participants want cigarettes and how much they are willing to work for them. The study also looks at how THC affects cigarette cravings, mood, heart rate, blood pressure, and thinking skills. You may be able to join if you are a healthy adult, aged 21 or older, who smokes cigarettes daily and uses cannabis at least once a week. Your cigarette use will be confirmed by a breath test (carbon monoxide level) and a urine test (cotinine). The study is currently unclear on its recruitment status and aims to enroll 100 participants.

Study design

This is an interventional study with 100 planned participants. It uses a double-blind, placebo-controlled, within-subjects crossover design, meaning neither you nor the researchers will know which dose of THC you receive, and you will receive all doses at different times.

What's involved

Not specified in the trial record.

Compensation

Not stated in the trial record.

Follow-up

The primary outcomes, Demand Intensity and Demand Elasticity, are measured 45 minutes after THC or placebo administration.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.