Study on Cannabis and E-Cigarette Use

This study is looking at how cannabis (THC) affects your desire to use e-cigarettes. Researchers want to understand how different doses of THC (0 mg, 5 mg, and 30 mg) impact your motivation, feelings, and body's response to e-cigarettes. You could be eligible if you are a healthy adult, 21 or older, who uses e-cigarettes daily and also uses cannabis at least once a week. To join, you'll need to have a positive urine cotinine test, which confirms e-cigarette use. The study will measure things like your craving for tobacco and how much you want e-cigarettes. The current status of this study is unclear, and it plans to enroll 100 participants.

Study design
This is a double-blind, placebo-controlled study, meaning neither you nor the researchers will know which dose of THC you are receiving. It involves comparing different doses of THC and a placebo within the same participants.
What's involved
Not specified in the trial record.
Compensation
Not stated in the trial record.
Follow-up
The primary outcomes, like demand intensity and elasticity, are measured 45 minutes after THC or placebo administration.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.

NCT06609109

Effect of Cannabis on E-Cigarette Use Behavior

Recruiting
PHASE1Ages 21+InterventionalBasic science
Johns Hopkins University
~100 participants
Updated 2026-04-09 on ClinicalTrials.gov
What's tested:THC High DoseTHC Low DoseTHC 0mgE-Cigarette Full NicotineE-Cigarette Placebo Nicotine

At a glance

Recruiting sites
1 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Demand Intensity
Measured over 45 minutes after THC or placebo administration
+1 more outcome measured
Cannabis Use
Tobacco Use
Electronic Cigarette Use
1 sites across 1 states
Maryland1
  • Dustin Lee, PhD · PRINCIPAL_INVESTIGATOR · Johns Hopkins School of Medicine

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  • Demand Intensity45 minutes after THC or placebo administration

    Consumption of e-cigarette puffs at unconstrained price as measured by an incentivized demand task. Minimum value is 0, maximum value is not constrained. Higher scores indicate more consumption at unconstrained price (a worse outcome).

  • Demand Elasticity45 minutes after THC or placebo administration

    Changes in e-cigarette consumption with changes in price as measured by an incentivized demand task. There is no minimum or maximum value. Higher scores indicate greater cigarette price sensitivity (a better outcome).