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CHEF Intervention for Childhood Cancer Survivors

This study is testing a program called the CHEF Intervention Program to help children and teenagers who have had cancer eat healthier. The program provides healthy meal kits and groceries, and helps families sign up for government food assistance programs like SNAP and WIC. The goal is to see if this program can improve dietary quality and support heart health in the long term. We are looking for children and teenagers up to 18 years old who have been treated for cancer with chemotherapy and/or radiation. Success will be measured by changes in dietary quality scores over 6 months. The current recruitment status is unclear.

Study design
This is an interventional study, meaning participants will receive the CHEF Intervention Program. About 17 participants are expected to join.
What's involved
You would be screened for eligibility, complete questionnaires, and have a brief interview. Participation is expected to last 6 months.
Compensation
Not stated in the trial record.
Follow-up
Dietary quality will be measured from baseline to 6 months.

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NCT06609473

Proof-of-Concept Testing of the Cardiovascular Health Equity Through Food (CHEF) Intervention in Childhood Cancer Survivors

Recruiting
NAUp to 18InterventionalSupportive care
Dana-Farber Cancer Institute
~17 participants
Updated 2026-04-13 on ClinicalTrials.gov
What's tested:CHEF Intervention Program

At a glance

Recruiting sites
2 of 2 listed sites are recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Change in Dietary Quality Score
Measured over From baseline to 6 months

Conditions

Childhood Cancer
Childhood Cancer Survivors

Explore related trials

Childhood Malignant Neoplasm

Where it's being run

2 sites across 1 states
Massachusetts2

Study leadership

  • Rahela Aziz-Bose, MD · PRINCIPAL_INVESTIGATOR · Dana-Farber Cancer Institute

Who to contact

Rahela Aziz-Bose, MD
[email protected]
617-632-3352
Email the study team

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Do you actually qualify for this trial?

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Eligibility criteria

Inclusion

Child with any primary cancer diagnosis (non-relapsed, non-secondary malignancy) who has received cancer-directed therapy that includes chemotherapy and/or radiation therapy;
Child is within one of the following time windows:
Child has 1 or more cardiovascular risk factor (defined as any of: body mass index ≥ 85th percentile; systolic or diastolic blood pressure ≥90th percentile; dyslipidemia \[triglycerides ≥150 mg/dL, total cholesterol ≥200 mg/dL, LDL cholesterol ≥130 mg/dL, HDL cholesterol ≤40 mg/dL\]; impaired glucose metabolism \[fasting glucose ≥100 mg/dL, hemoglobin A1c ≥5.7%\]; anthracycline exposure ≥100 mg/m2; or any radiation exposure to chest, brain, thoracic spine, or total body);
Child is ≤18 years of age at time of enrollment, or over 18 years of age but under medical guardianship;
Parent/guardian screened positive for food insecurity.\* \*Assessed through validated 2-item food insecurity screen.

Exclusion

Patient received only surgery, or watchful waiting/surveillance, for cancer- directed therapy;
Foreign national family receiving cancer care as an embassy-pay patient.

What this trial measures

  • Change in Dietary Quality ScoreFrom baseline to 6 months

    The change in mean participant dietary quality from study period T1 (baseline) to study period T3 (month 6), as measured by the Rapid Prime Dietary Quality Score Screener (scored 0-52, higher score indicates higher quality diet).