Understanding Muscle Response to Exercise in Older Adults
This study aims to understand how aging and inflammation might affect how your muscles respond to exercise. Researchers are looking at young and older adults (ages 21-85) who will perform a single bout of resistance exercise. The main goal is to see how your body's muscle-building response (anabolic response) changes after exercise, measured over two months. You cannot participate if you have diabetes, a BMI over 30, anemia, or active heart disease. The study is currently observational, meaning researchers will observe participants without assigning specific treatments, and the recruitment status is unclear.
- Study design
- This is an observational study involving 120 participants, including both young and older adults.
- What's involved
- Participants will perform a single session of unaccustomed resistance exercise. Researchers will assess muscle and fat tissue through biopsies and imaging.
- Compensation
- Not stated in the trial record.
- Follow-up
- The main outcome, anabolic response, will be measured at 2 months after the exercise.
AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.
Mechanisms of Anabolic Resistance in Older Humans
At a glance
Conditions
NCT06617195
Where you'd take part
This study runs at 1 site. They're the same protocol — you choose where, and that choice sets who your contact draft is addressed to.
Mayo Clinic
Rochester, Minnesotastudy coordinator listed
Recruiting
Sites open and close at different times, so the status above is per site — it can differ from the study's overall status.
Study leadership
- Ian Lanza · PRINCIPAL_INVESTIGATOR · Mayo Clinic
Who to contact
Opens a ready-to-send draft in your own email app — review before sending.
What this trial measures
- Anabolic response2 months
Skeletal muscle protein synthesis rates will be measured from isotopic enrichment of muscle proteins