Observational Study on Pain Inhibition in Chronic TMD Pain
This observational study is looking into why some people with chronic Temporomandibular Disorders (TMD) – conditions affecting the jaw and surrounding areas – might have trouble with their body's natural pain control system. Researchers will use "pain modulation testing" where they apply heat to your face and body to see how your body responds to pain. They want to understand how well your body can inhibit pain and how this relates to your daily pain levels. You can join if you are 18 to 74 years old and have chronic TMD. The study will measure how your body handles pain during a single visit and track your daily pain for 14 days. The current recruitment status is unclear.
- Study design
- This is an observational study planning to enroll 40 participants to understand pain inhibition in chronic TMD.
- What's involved
- You will have one in-person visit for pain modulation testing and will need to complete daily pain ratings for 7 days before and 7 days after the visit.
- Compensation
- Not stated in the trial record.
- Follow-up
- Your daily pain intensity will be tracked for 14 days (7 days before and 7 days after the in-person visit).
AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.
Endogenous Pain Inhibition Deficiency in Chronic TMD Pain
At a glance
Conditions
Where it's being run
1 sites across 1 statesStudy leadership
- Estephan Moana-Filho · PRINCIPAL_INVESTIGATOR · University of Minnesota
Who to contact
Opens a ready-to-send draft in your own email app — review before sending.
What this trial measures
- Conditioned pain modulation (CPM) effect3.5 hours single in-person visit
The CPM effect is manifested as a reduction of pain intensity evoked by a test stimulus (Ts) presented concurrently or right after a painful conditioning stimulus (Cs) applied to a distant body site.
- The relationship between daily pain intensity fluctuation and endogenous pain modulation (EPM) efficiency14 days: 7 days before and 7 days after the in-person visit
The daily presentation of chronic TMD pain is variable, especially in those presenting with pain that affects their daily activities. This variability could be partially attributed to the varying efficiency of EPM in this patient population.