This study is looking for adults aged 18-70 who are having elective heart surgery that uses a heart-lung machine (cardiopulmonary bypass). The goal is to see if taking CoQ10 and Glutathione can help prevent acute kidney injury (AKI), a serious complication after this type of surgery. You would either receive daily CoQ10 (1200 mg) and Glutathione (1000 mg) or a placebo (an inactive substance that looks like the real medication). The first dose is given the day before surgery and continues for up to one week while you are in the hospital. Doctors will measure if AKI happens at 28 and 90 days after surgery. To join, your kidney function (GFR) must be 45 ml/min or higher. The current recruitment status is unclear.

Study design

This is a double-blinded, randomized controlled trial, meaning neither you nor your doctor will know if you are receiving the active medications or the placebo. It plans to enroll 242 participants.

What's involved

You would take the study medication (CoQ10 and Glutathione or placebo) daily, starting the day before surgery and continuing for up to one week while hospitalized. Blood and urine samples will be collected.

Compensation

Not stated in the trial record.

Follow-up

Your kidney health will be checked at 28 days and 90 days after surgery.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.