Transnasal Sphenopalatine Ganglion Block for Headache After Brain Bleed
This study is testing a treatment for headaches that happen after a subarachnoid hemorrhage (SAH), which is a type of bleeding in the brain. Researchers want to see if adding a "transnasal sphenopalatine ganglion block" to standard pain medication helps reduce headache severity more than medication alone. This block involves using a device called Tx360 to deliver bupivacaine (a numbing medicine) and sometimes dexamethasone (an anti-inflammatory medicine) into your nose to reach a nerve cluster. The study is looking for 40 participants, aged 18 to 100, who have had an acute SAH and can describe their pain. You cannot join if you are pregnant, have an unsecured aneurysm, or cannot verbalize pain. The main goal is to see if this treatment reduces your pain scores. The study status is currently unclear.
- Study design
- This is a randomized controlled pilot study involving 40 participants. You would be assigned by chance to receive either standard pain medication or standard medication plus the sphenopalatine ganglion block.
- What's involved
- You would receive the sphenopalatine ganglion block procedure if you are in that group. Your pain scores and opioid use would be monitored from enrollment until ICU discharge, up to 14 days. Individual participation lasts up to four weeks.
- Compensation
- Not stated in the trial record.
- Follow-up
- Your pain scores will be measured from enrollment until ICU discharge, up to 14 days.
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Transnasal Sphenopalatine Ganglion Block for Treatment of Acute Subarachnoid Hemorrhage Associated Headache
At a glance
Conditions
Where it's being run
1 sites across 1 statesStudy leadership
- Christine Picinich, MS, AGACNP-BC, CCRN · PRINCIPAL_INVESTIGATOR · University of California, Davis
Who to contact
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Do you actually qualify for this trial?
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Inclusion
Exclusion
What this trial measures
- Numerical pain rating scaleFrom enrollment until ICU discharge, up to 14 days
Pain scores will be obtained at regular intervals to compare pain control between the two arms. Pain scores will be collected multiple times throughout each ICU day, up to ICU day 14.