Observational Study on Bone Changes After Tooth Extraction and Preservation

This study is looking at how your jawbone changes after a tooth is removed and a procedure called alveolar ridge preservation is done. This preservation helps keep the bone in place. Researchers want to see if the immediate changes in your tooth socket (like if it expands or stays the same width) affect how much your bone width and height change over 4 months. They will measure your bone width and height before extraction, right after, and then 4 months later. You might be able to join if you are between 18 and 75 years old, in good general health, have controlled gum disease, and are scheduled to have a single tooth extracted with a bone graft and a special membrane placed. The study is currently unclear on its recruitment status and plans to enroll 160 participants.

Study design
This is an observational study, meaning researchers will watch and record changes without giving you a specific treatment beyond your planned dental procedure. It aims to enroll 160 participants.
What's involved
You would have measurements taken before your tooth extraction, immediately after, and then 4 months later. Other information like your medical history and tooth details will also be recorded.
Compensation
Not stated in the trial record.
Follow-up
Participants will be followed for 4 months after tooth extraction and alveolar ridge preservation.

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NCT06624982

Determinants of Bone Dimensional Changes After Extraction and Alveolar Ridge Preservation

Recruiting
Not specifiedAges 18–75Observational
Marquette University
~160 participants
Updated 2025-11-17 on ClinicalTrials.gov
What's tested:observational study

At a glance

Recruiting sites
1 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Buccolingual ridge width
Measured over (1) After local anesthesia and before extraction, (2) immediately after extraction and (3) 4 months after extraction and alveolar ridge preservation
+1 more outcome measured
Alveolar Bone Grafting
Bone Healing
Tooth Extraction Site Healing
Wound Healing
1 sites across 1 states
Wisconsin1
  • Vrisiis Kofina, DDS, MS · PRINCIPAL_INVESTIGATOR · Marquette University

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Eligibility criteria

Inclusion

Adult patients (18-75 years)
Good general health (controlled conditions)
Controlled periodontal disease
Scheduled for single tooth extraction with bone graft placement and resorbable membrane
Tooth to be extracted must have adjacent teeth
Socket wall integrity

Exclusion

Smoking
Pregnancy
Active periodontal disease
Systemic conditions that affect healing
Lack of socket wall integrity (bone loss ≥50 %) prior to extraction, teeth with severe infection requiring pre-extraction antibiotic treatment to control infection), and contraindications for tooth extraction.
  • Buccolingual ridge width(1) After local anesthesia and before extraction, (2) immediately after extraction and (3) 4 months after extraction and alveolar ridge preservation

    Buccolingual ridge width will be measured through a stent via ridge mapping calipers. The measurement locations will be at 1mm, 3mm and 5mm from the midbuccal crest. The same measurements will be recorded at all selected time points.

  • Ridge height(1) After local anesthesia and before extraction, (2) immediately after extraction and (3) 4 months after extraction and alveolar ridge preservation

    Ridge height will be measured through a stent via a periodontal probe as the distance between bone and predetermined landmarks on the stent. The measurement locations will be mesial buccal, midbuccal, distal buccal, mesial lingual, midlingual and distal lingual. The same measurements will be recorded at all selected time points.