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Observational Study on Glioblastoma Outcomes

This observational study aims to understand what factors affect the health and risks for adults diagnosed with glioblastoma (GBM), a serious type of brain cancer. Researchers want to learn how genetics, the immune system, and your medical and work history might impact your survival and quality of life. You can join if you are at least 18 years old, have a confirmed diagnosis of glioblastoma, and can complete an online survey. The study will measure how long you live (Overall Survival) and your well-being using a questionnaire. This study does not involve any new treatments; it focuses on gathering information to help improve care for glioblastoma patients.

Study design
This is an observational study planning to enroll 200 participants with glioblastoma. It follows participants over time to see how different factors affect their health outcomes.
What's involved
You will fill out an online survey about your medical history and lifestyle. You will also have the option to provide a blood sample using a home collection kit.
Compensation
Not stated in the trial record.
Follow-up
Your overall survival will be tracked from enrollment until death, up to 60 months (5 years).

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.

NCT06625684

Key Longitudinal Associations With Risk and Glioblastoma Outcomes

Recruiting
Not specifiedAges 18+Observational
Duke University
~200 participants
Updated 2026-01-20 on ClinicalTrials.gov

At a glance

Recruiting sites
1 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Overall Survival
Measured over From date of enrollment until date of death from any cause as submitted by caregiver, up to 60 months
+1 more outcome measured

Conditions

Glioblastoma

Explore related trials

Glioblastoma

Where it's being run

1 sites across 1 states
North Carolina1

Study leadership

  • Quinn Ostrom, PhD · PRINCIPAL_INVESTIGATOR · Duke University

Who to contact

Quinn Ostrom, PhD
[email protected]
919 -684-5301
Email the study team

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Do you actually qualify for this trial?

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Eligibility criteria

Inclusion

At least 18 years old
Pathologically-confirmed diagnosis of glioblastoma multiforme (GBM) or grade 4 brain tumor
Participant is accessible for follow-up (has a working email address)
Participant is willing and able to comply with the study requirements

Exclusion

Those who cannot read either English or Spanish
Those who cannot view an online survey

What this trial measures

  • Overall SurvivalFrom date of enrollment until date of death from any cause as submitted by caregiver, up to 60 months

    Overall survival will be estimated using patient-reported date of diagnosis and assessed in three month intervals until patients are reported as deceased or are lost to follow-up

  • Functional Well-being as measured by the Functional Assessment of Cancer Therapy-Brain (FACT-Br) questionnaireAt time of study enrollment

    Estimated using the functional well-being subscale of the FACT-Br questionnaire. The score ranges from 0 to 28, where a higher score indicates greater functional well-being.