Exercise Effects on Stress-related Eating in Veterans
This study is looking at how exercise affects the brain's response to stress and food cues in veterans who are overweight or obese. You might be able to join if you are a veteran between 18 and 75 years old, have a body mass index (BMI) of 25 or higher, are not physically active, and can attend study visits in Aurora, CO. You cannot join if you are pregnant, have had bariatric surgery, have an eating disorder, or are taking medications that change your appetite. The study will measure changes in your brain's activity when you see food pictures (using fMRI, a type of brain scan) and your body's stress hormone (cortisol) levels after a thinking task. The study's status is currently unclear.
- Study design
- This is an interventional study planning to enroll 132 participants. Participants will be randomly assigned to either an exercise group or a usual activities group.
- What's involved
- You would complete two study days before and two study days after a 12-week period. If in the exercise group, you would complete exercise sessions four times per week during this 12-week period.
- Compensation
- Not stated in the trial record.
- Follow-up
- Your brain activity and cortisol levels will be measured at the beginning of the study and again after 12 weeks.
AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.
Exercise Effects on the Neurobiology Underlying Stress-related Eating Behaviors in Veterans
At a glance
Conditions
Where it's being run
1 sites across 1 statesStudy leadership
- Kristina T. Legget, PhD · PRINCIPAL_INVESTIGATOR · Rocky Mountain Regional VA Medical Center, Aurora, CO
Who to contact
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Do you actually qualify for this trial?
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Inclusion
Exclusion
What this trial measures
- Percent change in blood oxygen level dependent (BOLD) response to visual food cues as measured by functional magnetic resonance imaging (fMRI)Baseline, 12 weeks
Percent change in blood oxygen level dependent (BOLD) response from baseline to after the 12-week intervention period while viewing visual food cues. The primary contrast of interest is the comparison of high-calorie food images to nonfood object images.
- Change in serum cortisol response to counting taskBaseline, 12 weeks
Change from baseline to after the 12-week intervention period in serum cortisol levels (micrograms per deciliter (mcg/dL)) throughout a counting task involving mental math (measured as area under the curve).