Observational Study of Omaveloxolone (SKYCLARYS) During Pregnancy and Breastfeeding for Friedreich's Ataxia

This is an observational study to learn more about the health of women with Friedreich's Ataxia (FA) who took omaveloxolone (also known as BIIB141 or SKYCLARYS) during pregnancy or while breastfeeding. Researchers will also gather information about the health of their babies. This study will collect health information without changing your medical care. The main goal is to understand how omaveloxolone might affect pregnancy, the mother, and the baby, especially looking at major birth defects. You can join if you're a woman aged 16 or older who has taken omaveloxolone for FA at any point during pregnancy or breastfeeding.

Study design
This is an observational study, meaning it collects health information without changing your medical care. It aims to enroll 10 women.
What's involved
Not specified in the trial record.
Compensation
Not stated in the trial record.
Follow-up
The study will measure major congenital malformations (birth defects) for up to 10 years.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.

NCT06628687

A Study to Learn How BIIB141 (Omaveloxolone) Affects the Health of Participants With Friedrich's Ataxia Who Took it During Pregnancy and/or During Breastfeeding and About the Health of Their Babies

Recruiting
Not specifiedAges 16+Observational
Biogen
~10 participants
Updated 2026-07-10 on ClinicalTrials.gov
What's tested:Omaveloxolone

At a glance

Recruiting sites
1 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Number of Major Congenital Malformations (MCMs)
Measured over Up to 10 years
Friedreich Ataxia

NCT06628687

Where you'd take part

This study runs at 1 site. They're the same protocol — you choose where, and that choice sets who your contact draft is addressed to.

  • Evidera

    Morrisville, North Carolinastudy coordinator listed

    Recruiting

Sites open and close at different times, so the status above is per site — it can differ from the study's overall status.

  • Medical Director · STUDY_DIRECTOR · Biogen

Opens a ready-to-send draft in your own email app — review before sending.

  • Number of Major Congenital Malformations (MCMs)Up to 10 years

    A MCM is defined as an abnormality of body structure or function that is present at birth; is of prenatal origin (i.e., birth defect); has significant medical, social, or cosmetic consequences for the affected participant; and typically requires medical intervention.