AI-based Glaucoma Screening in Community Health Centers

This study is looking at how well an eye screening program works in Federally Qualified Health Centers (FQHCs), which are community health clinics. The program uses an artificial intelligence (AI) tool called AI-RONA to help screen for glaucoma and other eye problems like diabetic retinopathy (eye damage from diabetes), cataracts (cloudy eye lens), and vision loss. The study wants to see if this screening program helps identify people who might have these eye conditions and if they then go for follow-up eye exams. You might be able to join if you are African American or Hispanic and over 40, non-Hispanic white and over 50, or over 18 with diabetes or a family history of glaucoma. The study aims to enroll 1800 participants.

Study design
This interventional study plans to enroll 1800 participants. It will compare the rate of eye conditions detected with this screening program to clinics without the program.
What's involved
Participants will undergo glaucoma screening using an AI-algorithm, which includes an Artificial Intelligence Remote Optic Nerve Assessment (AI-RONA). The study measures outcomes up to 4 months.
Compensation
Not stated in the trial record.
Follow-up
Participants will be followed to see if they attend a follow-up eye exam by an optometrist or ophthalmologist, with this measured up to 4 months after screening.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.

NCT06629649

Implementing AI-based Glaucoma Screening Within Federally Qualified Health Centers

Recruiting
NAAges 18+InterventionalScreening
University of Alabama at Birmingham
~1,800 participants
Updated 2025-12-29 on ClinicalTrials.gov
What's tested:Glaucoma screening using an AI-algorithm and screening for diabetic retinopathy, cataract, and visual acuity impairment.

At a glance

Recruiting sites
1 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Rate of participants where the glaucoma screening protocol leads to a screening diagnosis of glaucoma
Measured over up to 2-3 days
+3 more outcomes measured
Glaucoma
Ocular Hypertension
1 sites across 1 states
Alabama1
  • Cynthia Owsley, PhD · PRINCIPAL_INVESTIGATOR · University of Alabama at Birmingham

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Eligibility criteria

Inclusion

African American or Hispanic persons ≥ 40 years old
Non-Hispanic white persons ≥ 50 years old
Anyone ≥ 18 years old with diabetes type 1 or type 2
Anyone ≥ 18 years old who already has a glaucoma associated disease
Anyone ≥ 18 years old with a family history of glaucoma

Exclusion

Declines to sign written informed consent
Cannot communicate in English
  • Rate of participants where the glaucoma screening protocol leads to a screening diagnosis of glaucomaup to 2-3 days

    Primary care provider will make a screening diagnosis of glaucoma associated disease based on the results of the screening

  • Rate of participants who decide to attend the follow up exam by optometrist or ophthalmologistup to 4 months

    If diagnosed with any of the above conditions, and primary car provider recommends follow-up care with an optometrist or ophthalmologist, whether participant actually attends the exam

  • Rate of participants where the screening protocol leads to a screening diagnosis of cataract, diabetic retinopathy, or visual acuity impairmentup to 2-3 days

    Based on results of screening, the primary care provider will be able to make a screening diagnosis of cataract, diabetic retinopathy or visual acuity impairment

  • Compare cost of screening program in FQHC to the cost of an ophthalmologist or optometrist guided assessmentup to 4 years

    Compare the cost of AI based interventions relying on optic disc photos alone, OCT alone, both imaging modalities, and imaging with standard vision tests performed by an ophthalmologist or optometrist guided program