Atorvastatin for Cardiovascular Risk After Hypertensive Disorders of Pregnancy

This study is looking at whether a medication called Atorvastatin (10 mg) can help reduce your risk of heart disease after you've experienced a hypertensive disorder of pregnancy (like gestational hypertension or preeclampsia). Researchers want to see if taking Atorvastatin for three months after breastfeeding stops can lower your 30-year Framingham Risk Score for Cardiovascular Disease. You might be able to join if you are a woman between 20 and 50 years old, are postpartum, and have been diagnosed with a hypertensive disorder of pregnancy. The study is currently recruiting 76 participants, but its overall status is unclear.

Study design
This is a double-blinded randomized controlled trial, meaning neither you nor your doctor will know if you're receiving Atorvastatin or a placebo. It plans to enroll 76 participants.
What's involved
You would take Atorvastatin 10 mg or a placebo daily for 3 months, starting after you stop breastfeeding. You will be followed for up to 1 year.
Compensation
Not stated in the trial record.
Follow-up
Participants will be followed for up to 1 year after the start of the study treatment.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.

NCT06632379

AtorvaStatin Postpartum and Reduction of Cardiovascular risK

Recruiting
PHASE4Ages 20–50InterventionalTreatment
Ohio State University
~76 participants
Updated 2025-10-20 on ClinicalTrials.gov
What's tested:Atorvastatin 10 mgPlacebo

At a glance

Recruiting sites
1 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
The 30-year Framingham Risk Score for Cardiovascular Disease
Measured over After 3 months of study treatment, up to 9 months after enrollment
Hypertensive Disorders of Pregnancy
Preeclampsia
Gestational Hypertension

NCT06632379

Where you'd take part

This study runs at 1 site. They're the same protocol — you choose where, and that choice sets who your contact draft is addressed to.

  • The Ohio State University Wexner Medical Center OB/GYN Maternal and Fetal Medicine

    Columbus, Ohiostudy coordinator listed

    Recruiting

Sites open and close at different times, so the status above is per site — it can differ from the study's overall status.

  • Tracy C Bank, MD · PRINCIPAL_INVESTIGATOR · Ohio State University

Opens a ready-to-send draft in your own email app — review before sending.

  • The 30-year Framingham Risk Score for Cardiovascular DiseaseAfter 3 months of study treatment, up to 9 months after enrollment

    Predicts 0-100% risk of "hard" CVD events (coronary death, myocardial infarction, stroke) based on sex, systolic blood pressure, antihypertensive treatment, total and high-density lipoprotein cholesterol, smoking, and diabetes mellitus. A higher number reflects a greater risk of adverse CVD events, whereas a lower number reflects lower risk.