Memory Training for Opioid Use Disorder
This study is looking into how memory works in people with opioid use disorder (OUD) and if a memory training program called MemFlex can help improve their symptoms and lives. MemFlex uses self-guided exercises to help you switch between specific and general memories, access positive memories, and make those positive memories feel more real. Everyone in the study will receive MemFlex. Researchers also want to understand how brain and heart activity are connected to memory and OUD symptoms. You may be able to join if you are 18 to 60 years old and willing to complete study visits and procedures. The study aims to enroll 30 participants and is currently recruiting.
- Study design
- This is an interventional study where all 30 participants will receive the MemFlex intervention. There is no placebo group.
- What's involved
- You will complete a baseline assessment, four weeks of at-home memory training, and a post-treatment follow-up assessment. Each visit will include a urine sample for drug testing.
- Compensation
- Not stated in the trial record.
- Follow-up
- Your autobiographical memory recall will be measured at the pre-treatment assessment (week 1) and post-treatment assessment (week 5).
AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.
Autobiographical Memory in Opioid Use Disorder
At a glance
Conditions
Where it's being run
1 sites across 1 statesWho to contact
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What this trial measures
- Autobiographical Memory (AM) Recall (AMT-AI)Pre and Post treatment assessment (weeks 1 and 5)
Specificity \[specific vs. general\] and valence \[positive, negative, neutral\] and PFC activity during AM recall.The AMT-AI outcomes will be the proportion of specific AMs in each condition (neutral, positive, negative) and mean ΔHbO in the mPFC and dlPFC (separately) during AM recall relative to the control block.