Understanding Rheumatic Side Effects from Immunotherapy

This study aims to understand the experiences of people who develop rheumatic immune-related adverse events (side effects like arthritis or polymyalgia rheumatica) after receiving immune checkpoint inhibitor immunotherapy. Researchers want to learn about the severity and impact of these side effects on your daily life. You may be able to join if you are 18 or older, speak English, and have a diagnosis from a rheumatologist of inflammatory arthritis or polymyalgia rheumatica that developed after immune checkpoint inhibitor therapy. The study will measure safety and adverse events over an average of one year to see what success looks like. The current recruitment status is unclear.

Study design
This is an observational study, meaning researchers will gather information without giving any specific treatments. It plans to include about 20 participants.
What's involved
Not specified in the trial record.
Compensation
Not stated in the trial record.
Follow-up
Participants will be followed through study completion, which is an average of one year.

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NCT06647134

A Qualitative Assessment of the Severity and Impact of Rheumatic Immune-Related Adverse Events Following Immune Checkpoint Inhibitor Immunotherapy

Recruiting
Not specifiedAges 18+Observational
M.D. Anderson Cancer Center
~20 participants
Updated 2026-04-13 on ClinicalTrials.gov

At a glance

Recruiting sites
1 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Safety and Adverse Events (AEs).
Measured over Through study completion; an average of 1 year
Arthritis
Polymyalgia Rheumatica
Immune Checkpoint Inhibitors
1 sites across 1 states
Texas1
  • Y. Jeff Li, MD · PRINCIPAL_INVESTIGATOR · M.D. Anderson Cancer Center

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Eligibility criteria

Inclusion

Patients aged 18 years and above
English (conversational level) speaking, with the ability to give informed consent
Patients with a rheumatologist clinician diagnosis of inflammatory arthritis irAE or PMR irAE following ICI therapy

Exclusion

Acutely life-threatening or worsening cancer
Hearing impairment functionally limiting participation in verbal interview
  • Safety and Adverse Events (AEs).Through study completion; an average of 1 year

    Incidence of Adverse Events