CurePSP Genetics Program for PSP, CBS, and related conditions
This study, called The CurePSP Genetics Program, is looking for up to 1,000 adults who have been diagnosed with Progressive Supranuclear Palsy (PSP), Corticobasal Syndrome (CBS), or related neurological conditions. Unaffected family members with a family history of these conditions can also join. The goal is to collect DNA samples to better understand the genetic causes of these diseases. Researchers will perform whole genome sequencing (looking at all of your genes) on blood samples at the National Institutes of Health. This research aims to improve diagnosis, guide genetic counseling, and help find new treatments. The study is observational, meaning it involves collecting information without giving any new treatments, and involves minimal risk.
- Study design
- This is an observational study aiming to enroll up to 1,000 participants. It is not specified if it is randomized or blinded.
- What's involved
- Participants will provide blood samples for whole genome sequencing. The study involves minimal risk.
- Compensation
- Not stated in the trial record.
- Follow-up
- Whole genome sequencing results will be measured at 5 years.
AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.
The CurePSP Genetics Program
At a glance
Conditions
Where it's being run
1 sites across 1 statesWho to contact
Opens a ready-to-send draft in your own email app — review before sending.
What this trial measures
- Whole genome sequencing5 years
All samples will first undergo non-CLIA approved whole genome sequencing on a research basis in collaboration with Sonja Scholz, MD, PhD at the Neurodegenerative Diseases Research Unit of the National Institutes of Health (Bethesda, MD). This sequencing method allows for the identification of not only variants known to be associated with these disorders but also potentially novel variants.