Studying Plectin for Cholangiocarcinoma Diagnosis

This study is looking for a better way to diagnose cholangiocarcinoma (a type of bile duct cancer). Currently, diagnosing this cancer can be difficult, and many patients are diagnosed too late for a cure. Researchers are investigating if detecting a protein called plectin on the surface of cells from bile duct samples can help diagnose cholangiocarcinoma more accurately. You may be able to join if you are 18 or older, have a bile duct stricture (narrowing) or mass seen on imaging, and are already scheduled for an ERCP (Endoscopic Retrograde Cholangiopancreatography, a procedure to examine bile ducts). The study will consider it a success if positive plectin staining is found in these samples. The current recruitment status is unclear.

Study design
This is an observational study, meaning researchers will collect information without giving any new treatments. It aims to include 100 participants.
What's involved
Not specified in the trial record.
Compensation
Not stated in the trial record.
Follow-up
Plectin staining will be measured at 2 years.

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NCT06651346

Cell-Surface Plectin in the Diagnosis of Cholangiocarcinoma from ERCP-directed Biliary Samples

Not Yet Recruiting
Not specifiedAges 18+Observational
University of Virginia
~100 participants
Updated 2025-01-30 on ClinicalTrials.gov

At a glance

Recruiting sites
0 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Positive plectin staining on IHC from ERCP-directed biliary samples
Measured over 2 years
Cholangiocarcinoma
1 sites across 1 states
Virginia1

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Do you actually qualify for this trial?

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Eligibility criteria

Inclusion

Biliary stricture or mass seen on imaging; already undergoing ERCP as part of their routine clinical care

Exclusion

Age \< 18 years old; inability to consent
  • Positive plectin staining on IHC from ERCP-directed biliary samples2 years

    Positive plectin staining on IHC from ERCP-directed biliary samples