Ketorolac and Lidocaine for Pain During Hysteroscopy

This study is looking at ways to reduce pain during an office hysteroscopy (a procedure to examine the inside of the uterus). Researchers are comparing two types of paracervical block (a local anesthetic injection near the cervix): one with lidocaine only, and another with both lidocaine and ketorolac (an anti-inflammatory pain medication). The goal is to see if adding ketorolac helps more with pain during the procedure. You might be able to join if you are a woman, at least 18 years old, and scheduled for an office hysteroscopy at Mount Sinai Hospital faculty practice associates. You cannot join if you have allergies to lidocaine or ketorolac, or certain other medical conditions. The study aims to enroll 60 participants. The current recruitment status is unclear.

Study design
This is a randomized, double-blind, placebo-controlled study involving 60 participants. This means participants are randomly assigned to receive one of the two treatments, and neither you nor your doctor will know which treatment you are receiving.
What's involved
Not specified in the trial record.
Compensation
Not stated in the trial record.
Follow-up
Pain levels will be measured during the procedure, immediately after, and 30 minutes after the procedure.

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NCT06653400

Combined Ketorolac and Lidocaine Paracervical Block for Office Hysteroscopy

Recruiting
PHASE1Ages 18+InterventionalTreatment
Icahn School of Medicine at Mount Sinai
~60 participants
Updated 2025-10-31 on ClinicalTrials.gov
What's tested:paracervical blockLidocaineketorolac

At a glance

Recruiting sites
1 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Pain visual analogue scale (VAS)
Measured over during procedure (cervical dilation)
Abnormal Uterine Bleeding
Analgesia
Paracervical Block
1 sites across 1 states
New York1
  • Charles Ascher-Walsh, MD · PRINCIPAL_INVESTIGATOR · Icahn School of Medicine at Mount Sinai

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Eligibility criteria

Inclusion

Patients assigned female at birth,
booked for office hysteroscopy at Mount Sinai Hospital faculty practice associates.

Exclusion

Allergy to ketorolac or non-steroidal anti-inflammatory medications
Allergy to lidocaine
Presence of thrombocytopenia
Contraindications to lidocaine
History of gastritis or gastric ulcer
Acute renal failure or chronic renal disease
Chronic liver disease
History of bleeding diathesis
Long term narcotic use
  • Pain visual analogue scale (VAS)during procedure (cervical dilation)

    Pain as measured on a 100 mm visual analogue scale (VAS) with cervical dilation. Full scale scored from 0-100, higher score indicates more pain.