Supplemental Bupivacaine After Root Canal Treatment

This study is looking at whether an extra injection of bupivacaine, a long-lasting numbing medicine, after a root canal (non-surgical endodontic treatment) can help reduce pain, improve your quality of life, and decrease the amount of pain medication you need. You might receive bupivacaine, a mock injection (placebo), or no additional injection. Researchers will compare these groups to see if bupivacaine makes a difference. To join, you must be at least 18 years old, have good general health (ASA Class I or II), and be scheduled for a root canal for a specific type of tooth pain. The main goal is to see how your quality of life changes after treatment, measured over five days. The current status of this study is unclear, and it plans to enroll 150 people.

Study design
This is an interventional study comparing bupivacaine to a placebo injection and no injection. It plans to enroll 150 participants.
What's involved
You would receive an additional injection (bupivacaine or placebo) or no additional injection after your root canal. Your quality of life will be measured on the day of your operation and daily for four days afterward.
Compensation
Not stated in the trial record.
Follow-up
Your quality of life will be measured for four days immediately following your endodontic treatment.

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NCT06655454

Supplemental Postoperative Bupivacaine Following Non-Surgical Endodontic Treatment

Recruiting
PHASE2Ages 18+InterventionalSupportive care
New York University
~150 participants
Updated 2026-04-13 on ClinicalTrials.gov
What's tested:Supplemental Postoperative BupivacainePlacebo Injection

At a glance

Recruiting sites
1 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Quality of life (scored based on the OHIP-14 questionnaire)
Measured over Day of operation and daily for four days immediately following endodontic treatment
Pain Assessment
Quality of Life (QOL)
Analgesic Use
1 sites across 1 states
New York1

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  • Quality of life (scored based on the OHIP-14 questionnaire)Day of operation and daily for four days immediately following endodontic treatment

    Quality of life will be measured with a modified version of the OHIP-14 questionnaire. For each question, the answers correspond with a scale that runs from 0-4. A higher score corresponds with a lower quality of life, with 0 being great quality of life and 4 being very poor quality of life.