This study is looking at how exercise and beetroot juice affect people with Peripheral Artery Disease (PAD), a condition where narrowed arteries reduce blood flow to your limbs. We want to see if a 12-week supervised exercise program increases a substance called nitrite in your body. We're also studying if adding nitrate-rich beetroot juice to exercise helps those who don't respond well to exercise alone. You might be able to join if you are 50 or older and have PAD, confirmed by specific tests like an ABI (Ankle-Brachial Index) measurement. The study aims to enroll 200 participants.

Study design

This is a randomized trial involving 200 participants. You would be assigned to one of several groups: supervised treadmill exercise, educational sessions, beetroot juice plus exercise, or placebo plus exercise.

What's involved

You would participate in either supervised treadmill exercise three times a week for 12 weeks, or attend weekly educational sessions for 12 weeks. If in a combination group, you would drink beetroot juice or a placebo while exercising.

Compensation

Not stated in the trial record.

Follow-up

Your nitrite levels will be measured at 12 weeks. Your walking ability (Six-minute walk) will be measured at 12 weeks and again at 24 weeks.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.