A Phase 2 Study of CRD-4730 in CPVT

{ "Phase 2 Study of CRD-4730 for CPVT", "This study is testing an investigational medicine called CRD-4730 for people with Catecholaminergic Polymorphic Ventricular Tachycardia (CPVT). CPVT is a heart condition that can cause dangerous heart rhythms. The study aims to understand how safe CRD-4730 is, how well your body handles it, and its effects. You may be able to join if you are 18 or older and have a confirmed CPVT diagnosis, including a specific genetic mutation (RYR2). The study will compare different doses of CRD-4730 with a placebo (an inactive pill that looks like the study medicine). The main goal is to look at changes from the start of the study up to Day 101.", "design": "This is a Phase 2, randomized, double-blind, placebo-controlled study with 12 participants. It involves comparing two doses of CRD-4730 with a placebo.", "commitments": "You will receive two different doses of CRD-4730 and one dose of a matching placebo over three periods. The primary outcomes are measured from Baseline to Day 101.", "compensation": "Not stated in the trial record.", "follow_up": "The primary outcomes are measured up to Day 101 after the start of the study.", }

Study design
Not specified.
What's involved
Not specified in the trial record.
Compensation
Not stated in the trial record.
Follow-up
Not specified.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.

NCT06658899

A Phase 2 Study of CRD-4730 in CPVT

Recruiting
PHASE2Ages 18–99InterventionalTreatment
Cardurion Pharmaceuticals, Inc.
~12 participants
Updated 2026-07-09 on ClinicalTrials.gov
What's tested:CRD-4730Placebo

At a glance

Recruiting sites
12 of 12 listed sites are recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Primary Outcome Measures
Measured over Baseline to Day 101
Catecholaminergic Polymorphic Ventricular Tachycardia
12 sites across 10 states
France3
California1
North Carolina1
Texas1
Utah1
Wisconsin1
British Columbia1
Pavia1

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  • Primary Outcome MeasuresBaseline to Day 101

    The number and severity of treatment-emergent adverse events (TEAEs) related to study drug treatment