Ketamine Oral Rinse for Pain from Oral Mucositis in Head and Neck Cancer
This study is looking at whether a ketamine oral rinse can help reduce pain from oral mucositis (mouth sores) in people with head and neck cancer who are receiving radiation treatment. You would be given either the ketamine oral rinse or an unmedicated syrup (placebo) to use four times a day, in addition to your standard care. The study aims to see how many patients experience a change in their pain from mucositis after using the ketamine oral rinse. To join, you must be at least 18 years old and have head and neck cancer that is being treated with radiation or chemoradiation. The study is currently unclear on its recruitment status.
- Study design
- This is a two-arm study that plans to enroll 62 participants. Participants will be randomly assigned to receive either ketamine oral rinse or an unmedicated oral rinse.
- What's involved
- If you develop oral mucositis during radiation, you would use the assigned oral rinse four times a day. You would also keep a pain diary daily and be monitored during treatment and for up to 30 days afterward.
- Compensation
- Not stated in the trial record.
- Follow-up
- Participants will be monitored during treatment and for up to 30 days after, with the primary outcome measured at 6 months.
AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.
Head and Neck Cancer Patients With Oral Mucositis Treated With Ketamine Oral Rinse
At a glance
Conditions
Where it's being run
1 sites across 1 statesStudy leadership
- Rusha Patel, MD · PRINCIPAL_INVESTIGATOR · OU Health Stephenson Cancer Center
Who to contact
Opens a ready-to-send draft in your own email app — review before sending.
What this trial measures
- Number of patients who have altered pain response from mucositis in head and neck cancer undergoing radiation treatment from using ketamine oral rinse.6 months
Review weekly questionnaires of patients who received ketamine oral rinse to assess if it helped with the pain of mucositis caused by the radiation in head and neck cancer patients.